In the face of an “epidemic” increase in myopia over the last decades and myopia
prevalence predicted to reach 2.5 billion people by the end of this decade, there is an urgent …

The anterior pituitary gland has the ability to respond to complex signals derived from central
and peripheral systems. Perception of these signals and their integration are mediated by …

Background Dopamine agonist resistance in prolactinoma is an infrequent phenomenon.
Doses of cabergoline (CAB) of up to 2.0 mg/week are usually effective in controlling …

Pituitary adenomas cause significant endocrine and mass-related morbidity. Little is known
about the mechanisms that underlie pituitary tumor pathogenesis. In the present study, we …

Previous studies in an experimental mouse model of endometriosis have shown that the
dopamine agonist (DA) cabergoline (Cb2) reduces angiogenesis and endometriotic lesions …

Pituitary tumorigenesis is highly prevalent and causes major endocrine disorders. Hardly
anything is known on the behavior of the local stem cells in this pathology. Here, we …

Prolactinomas are the most frequently observed pituitary adenomas and most of them
respond well to conventional treatment with dopamine agonists (DAs). However, a subset of …

Pituitary tumors are usually less vascularized than the normal pituitary, and the role of
angiogenesis in these adenomas is contentious. Appraisal of microvascular density and …

The role of angiogenesis in pituitary tumor development has been questioned, as pituitary
tumors have been usually found to be less vascularized than the normal pituitary tissue …

Conserved signaling pathways are critical regulators of pituitary homeostasis and, when
dysregulated, contribute to adenoma formation. Pituitary adenomas are typically benign and …