Adult animal stem cell-derived organoids in biomedical research and the one health paradigm

V Gabriel, C Zdyrski, DK Sahoo, A Ralston… - International journal of …, 2024 - mdpi.com
Preclinical biomedical research is limited by the predictiveness of in vivo and in vitro models.
While in vivo models offer the most complex system for experimentation, they are also …

The roles of extracellular vesicles and organoid models in female reproductive physiology

RE Thompson, GJ Bouma, FK Hollinshead - International Journal of …, 2022 - mdpi.com
Culture model systems that can recapitulate the anatomy and physiology of reproductive
organs, such as three-dimensional (3D) organoid culture systems, limit the cost and welfare …

Endometrial receptivity and embryo implantation in carnivores—commonalities and differences with other mammalian species

EE Paulson, P Comizzoli - Biology of reproduction, 2021 - academic.oup.com
Endometrial receptivity and embryo implantation processes are a major point of pregnancy
failure in many mammalian species, including humans. Although reproductive biology in …

Improved models of human endometrial organoids based on hydrogels from decellularized endometrium

E Francés-Herrero, E Juárez-Barber, H Campo… - Journal of personalized …, 2021 - mdpi.com
Organoids are three-dimensional (3D) multicellular tissue models that mimic their
corresponding in vivo tissue. Successful efforts have derived organoids from primary tissues …

Organoids for toxicology and genetic toxicology: applications with drugs and prospects for environmental carcinogenesis

AL Caipa Garcia, VM Arlt, DH Phillips - Mutagenesis, 2022 - academic.oup.com
Advances in three-dimensional (3D) cell culture technology have led to the development of
more biologically and physiologically relevant models to study organ development, disease …

Companion animal organoid technology to advance veterinary regenerative medicine

LC Penning, R van den Boom - Frontiers in Veterinary Science, 2023 - frontiersin.org
First year medical and veterinary students are made very aware that drugs can have very
different effects in various species or even in breeds of one specific species. On the other …

Decidual cells and decidualization in the carnivoran endotheliochorial placenta

ME Diessler, R Hernández, G Gomez Castro… - Frontiers in Cell and …, 2023 - frontiersin.org
Decidualization is considered a distinctive feature of eutherian pregnancy, and has
appeared during evolution along with the development of invasive forms of placentation, as …

Collagen-based biomaterials in organoid technology for reproductive medicine: Composition, characteristics, and applications

B Feng, H Yang, M Zhu, J Li, HM Chang… - Collagen and …, 2023 - Springer
Collagen-based biomaterials (CBB) are highly esteemed by researchers in materials
science and biomedicine due to their extensive applications across various biomedical …

Endometrial Determinism of Endometriosis: An Unnecessary Adjunct to Retrograde Menstruation

M Habiba, SW Guo, G Benagiano - Current Obstetrics and Gynecology …, 2024 - Springer
Abstract Purpose of Review The observation that retrograde menstruation is almost
universal while only a small proportion of women suffer with endometriosis is among the …

Advances in the use of organoids in endometrial diseases

Y Liu, Y Sun, S Cheng - International Journal of Gynecology & …, 2024 - Wiley Online Library
The endometrium undergoes cyclical changes in response to hormones and there is a
certain degree of heterogeneity among individuals. In vivo identification of the physiologic …