A multidisciplinary approach remains the best strategy to improve and strengthen the management of ovarian cancer

L Falzone, G Scandurra… - International …, 2021 - spandidos-publications.com
Ovarian cancer represents one of the most aggressive female tumors worldwide. Over the
decades, the therapeutic options for the treatment of ovarian cancer have been improved …

The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study

G Funston, W Hamilton, G Abel, EJ Crosbie… - PLoS …, 2020 - journals.plos.org
Background The serum biomarker cancer antigen 125 (CA125) is widely used as an
investigation for possible ovarian cancer in symptomatic women presenting to primary care …

Identifying ovarian cancer in symptomatic women: a systematic review of clinical tools

G Funston, V Hardy, G Abel, EJ Crosbie, J Emery… - Cancers, 2020 - mdpi.com
Simple Summary Most women with ovarian cancer are diagnosed after they develop
symptoms—identifying symptomatic women earlier has the potential to improve outcomes …

[HTML][HTML] Association between purchase of over-the-counter medications and ovarian cancer diagnosis in the cancer loyalty card study (CLOCS): observational case …

HR Brewer, Y Hirst, M Chadeau-Hyam… - JMIR public health …, 2023 - publichealth.jmir.org
Background: Over-the-counter (OTC) medications are frequently used to self-care for
nonspecific ovarian cancer symptoms prior to diagnosis. Monitoring such purchases may …

The performance of HE4 alone and in combination with CA125 for the detection of ovarian cancer in an enriched primary care population

CE Barr, G Funston, D Jeevan, S Sundar, LTA Mounce… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most common cause of death from gynaecological
cancer in the UK. Survival is better when the disease is diagnosed early. However …

Current methods for identifying plasma membrane proteins as cancer biomarkers

E Jong, A Kocer - Membranes, 2023 - mdpi.com
Plasma membrane proteins are a special class of biomolecules present on the cellular
membrane. They provide the transport of ions, small molecules, and water in response to …

CA125 test result, test-to-diagnosis interval, and stage in ovarian cancer at diagnosis: A retrospective cohort study using electronic health records

G Funston, LTA Mounce, S Price, B Rous… - British Journal of …, 2021 - bjgp.org
Background In the UK, the cancer antigen 125 (CA125) test is recommended as a first-line
investigation in women with symptoms of possible ovarian cancer. Aim To compare time …

Role of primary care physician factors on diagnostic testing and referral decisions for symptoms of possible cancer: a systematic review

V Hardy, A Yue, S Archer, SWD Merriel, M Thompson… - BMJ open, 2022 - bmjopen.bmj.com
Background Missed opportunities for diagnosing cancer cause patients harm and have
been attributed to suboptimal use of tests and referral pathways in primary care. Primary …

Reclassification of patients with ambiguous CA125 for optimised pre-surgical triage

AN Stephens, SJ Hobbs, SW Kang, MK Oehler… - Diagnostics, 2024 - mdpi.com
Pre-surgical clinical assessment of an adnexal mass is a complex process, and ideally
requires accurate and rapid identification of disease status. Gold standard biomarker CA125 …

Insight on Non-Coding RNAs from Biofluids in Ovarian Tumors

Y Dabi, A Favier, L Razakamanantsoa, L Delbos… - Cancers, 2023 - mdpi.com
Simple Summary Ovarian cancer is the most lethal gynecologic cancer since it is often
diagnosed at advanced stages. Current tools for diagnosis are currently insufficient and …