Lanthanide probes for bioresponsive imaging

MC Heffern, LM Matosziuk, TJ Meade - Chemical reviews, 2014 - ACS Publications
The chemistry of the less familiar elements is a fascinating topic especially for the inorganic
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …

Emerging concepts in dendrimer‐based nanomedicine: from design principles to clinical applications

RM Kannan, E Nance, S Kannan… - Journal of internal …, 2014 - Wiley Online Library
Dendrimers are discrete nanostructures/nanoparticles with 'onion skin‐like'branched layers.
Beginning with a core, these nanostructures grow in concentric layers to produce stepwise …

Chemical exchange saturation transfer (CEST): what is in a name and what isn't?

PCM Van Zijl, NN Yadav - Magnetic resonance in medicine, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is a relatively new magnetic
resonance imaging contrast approach in which exogenous or endogenous compounds …

Rare earths: jewels for functional materials of the future

SV Eliseeva, JCG Bünzli - New Journal of Chemistry, 2011 - pubs.rsc.org
In recent decades, rare earths have become vital to a wealth of advanced materials and
technologies including catalysts, alloys, magnets, optics and lasers, rechargeable hydride …

Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7 T

CK Jones, A Huang, J Xu, RAE Edden, M Schär, J Hua… - Neuroimage, 2013 - Elsevier
Chemical exchange saturation transfer (CEST) is a magnetization transfer (MT) technique to
indirectly detect pools of exchangeable protons through the water signal. CEST MRI has …

Natural D‐glucose as a biodegradable MRI contrast agent for detecting cancer

KWY Chan, MT McMahon, Y Kato, G Liu… - Magnetic resonance …, 2012 - Wiley Online Library
Purpose: Modern imaging technologies such as CT, PET, SPECT, and MRI employ contrast
agents to visualize the tumor microenvironment, providing information on malignancy and …

Nuts and bolts of chemical exchange saturation transfer MRI

G Liu, X Song, KWY Chan… - NMR in Biomedicine, 2013 - Wiley Online Library
Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast
mechanism that is well suited for molecular imaging studies. This new mechanism can be …

Evaluations of extracellular pH within in vivo tumors using acidoCEST MRI

LQ Chen, CM Howison, JJ Jeffery… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose A practical, noninvasive method is needed to measure the extracellular pH (pHe)
within in vivo tumors to longitudinally monitor tumor acidosis. We have optimized a …

Quantitative tissue pH measurement during cerebral ischemia using amine and amide concentration-independent detection (AACID) with MRI

N McVicar, AX Li, DF Goncalves… - Journal of Cerebral …, 2014 - journals.sagepub.com
Tissue pH is an indicator of altered cellular metabolism in diseases including stroke and
cancer. Ischemic tissue often becomes acidic due to increased anaerobic respiration …

A review of optimization and quantification techniques for chemical exchange saturation transfer MRI toward sensitive in vivo imaging

J Kim, Y Wu, Y Guo, H Zheng… - Contrast media & …, 2015 - Wiley Online Library
Chemical exchange saturation transfer (CEST) MRI is a versatile imaging method that
probes the chemical exchange between bulk water and exchangeable protons. CEST …