Pharmaceutical hydrates analysis—overview of methods and recent advances

E Jurczak, AH Mazurek, Ł Szeleszczuk, DM Pisklak… - Pharmaceutics, 2020 - mdpi.com
This review discusses a set of instrumental and computational methods that are used to
characterize hydrated forms of APIs (active pharmaceutical ingredients). The focus has been …

Removal of carbamazepine, diclofenac and trimethoprim by solar driven advanced oxidation processes in a compound triangular collector based reactor: A …

K Kowalska, G Maniakova, M Carotenuto, O Sacco… - Chemosphere, 2020 - Elsevier
Contaminants of emerging concern (including pharmaceuticals) are not effectively removed
by municipal wastewater treatment plants (WWTPs), so particular concern is related to …

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: physicochemical characterization and in vitro/in vivo evaluation

SS Montoto, ML Sbaraglini, A Talevi… - Colloids and Surfaces B …, 2018 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) represent promising
alternatives for drug delivery to the central nervous system. In the present work, four different …

Pharmaceutical load in sewage sludge and biochar produced by hydrothermal carbonization

C Vom Eyser, K Palmu, TC Schmidt, J Tuerk - Science of the Total …, 2015 - Elsevier
We investigated the removal of twelve pharmaceuticals in sewage sludge by hydrothermal
carbonization (HTC), which has emerged as a technology for improving the quality of …

Rethinking carbamazepine oral delivery using polymer-lipid hybrid nanoparticles

R Ana, M Mendes, J Sousa, A Pais, A Falcão… - International journal of …, 2019 - Elsevier
Epilepsy is the most common chronic brain disorder and affects millions of people
worldwide. Carbamazepine (CBZ) is one of the first-line pharmacological therapy instituted …

Carbamazepine/tartaric acid cocrystalline forms: When stoichiometry and synthesis method matter

L Roca-Paixão, NT Correia, F Danede… - Crystal Growth & …, 2022 - ACS Publications
A deep investigation of the cocrystallization of carbamazepine form III (CBZ) with dl-tartaric
acid (dl-TA) and l-tartaric acid (l-TA) has been undertaken. Different methods of synthesis …

Crystallization tendency of APIs possessing different thermal and glass related properties in amorphous solid dispersions

A Kapourani, E Vardaka, K Katopodis… - International Journal of …, 2020 - Elsevier
The correlation between glass forming ability (GFA) and several thermophysical or
physicochemical properties of APIs with the formation and the physical stability of …

Pyrolysis of biosolids as an effective tool to reduce the uptake of pharmaceuticals by plants

F Mercl, Z Košnář, P Maršík, M Vojtíšek, J Dušek… - Journal of Hazardous …, 2021 - Elsevier
Biosolids were applied as a fertilizer after drying, torrefaction (220, 320° C), and pyrolysis
(420, 520, 620° C). Lettuce was grown on contrasting soils, and the transfer of …

Cold-crystallization and physical stability of glassy carbamazepine

A Dołęga, E Juszyńska-Gałązka, A Deptuch, S Baran… - Thermochimica …, 2022 - Elsevier
Physical stability as well as isothermal and non-isothermal cold-crystallization of quench-
cooled drug carbamazepine (CBZ) was studied using powder X-ray diffraction (XRD) …

Heat capacities of selected active pharmaceutical ingredients

V Štejfa, V Pokorný, A Mathers, K Růžička… - The Journal of Chemical …, 2021 - Elsevier
Condensed-phase heat capacities of selected pharmaceutical active pharmaceutical
ingredients (APIs), namely (RS)-ibuprofen (CAS RN: 15687-27-1),(S)-ibuprofen (CAS RN …