Population (Sanger) sequencing has been the standard method in basic and clinical DNA
sequencing for almost 40 years; however, next-generation (deep) sequencing …

The human immunodeficiency virus (HIV) persists in latently infected CD4+ T cells and
integrates with the host genome until cell death. Acquired immunodeficiency syndrome …

Next generation sequencing (NGS) is a trending new standard for genotypic HIV-1 drug
resistance (HIVDR) testing. Many NGS HIVDR data analysis pipelines have been …

Background The presence of high-abundance drug-resistant HIV-1 jeopardizes success of
antiretroviral therapy (ART). Despite numerous investigations, the clinical impact of low …

Conventional HIV drug resistance (HIVDR) genotyping utilizes Sanger sequencing (SS)
methods, which are limited by low data throughput and the inability of detecting low …

Introduction Next‐generation sequencing (NGS) has several advantages over conventional
Sanger sequencing for HIV drug resistance (HIVDR) genotyping, including detection and …

Background: There are an increasing number of articles focused on the prevalence and
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …

Identifying HCV drug resistance mutations (DRMs) is increasingly important as new direct
acting antiviral therapies (DAA) become available. Tagged pooled pyrosequencing (TPP) …

Objectives Increased trends of primary drug resistance mutations (DRMs) among treatment-
naive HIV-1-infected patients in low-and middle-income countries (LMICs) and the non …

Objectives This study investigated strategies that may increase the yield of drug resistance
testing prior to starting antiretroviral therapy (ART), and whether transmitted and …