Herpes simplex viruses (HSV) types 1 and 2 are ubiquitous infections in humans. They
cause orofacial and genital herpes with occasional severe complications. HSV2 also …

Herpes Simplex Virus (HSV) is a highly prevalent sexually transmitted infection that aside
from causing cold sores and genital lesions, causes complications in the …

All circulating immunoglobulin G (IgG) antibodies in human newborns are of maternal origin
and transferred across the placenta to provide passive immunity until newborn IgG …

HSV-1 causes 50% of first-time genital herpes infections in resource-rich countries and
affects 190 million people worldwide. A prophylactic herpes vaccine is needed to protect …

Neonatal herpes simplex virus (nHSV) infections cause devastating morbidity and mortality
in infants. Most nHSV cases are associated with primary maternal infection, consistent with …

Tissue-based T cells are important effectors in the prevention and control of mucosal viral
infections; less is known about tissue-based B cells. We demonstrate that B cells and …

The fetal/neonatal period represents both a unique window of opportunity for interventions
as well as vulnerability to a number of viral infections. While Herpesviruses such as herpes …

The cornea is essential for vision yet highly sensitive to immune-mediated damage following
infection. Generating vaccines that provide sterile immunity against ocular surface …

Herpes simplex virus (HSV) can cause severe infection in neonates leading to mortality and
lifelong morbidity. Prophylactic approaches, such as maternal immunization, could prevent …

Background Genetics have provided hints on potential molecular pathways involved in
neurodegenerative diseases (NDD). However, the number of cases caused exclusively by …