Protective effect of RA on myocardial infarction-induced cardiac fibrosis via AT1R/p38 MAPK pathway signaling and modulation of the ACE2/ACE ratio

Q Liu, J Tian, Y Xu, C Li, X Meng… - Journal of agricultural and …, 2016 - ACS Publications
Rosmarinic acid (α-o-caffeoyl-3, 4-dihydroxyphenyllactic acid, RA) is a major active
constituent of Rosmarinus officinalis Linn.(rosemary) having significant anti-inflammatory …

Regenerative cross talk between cardiac cells and macrophages

AJ Whitehead, AJ Engler - American Journal of Physiology …, 2021 - journals.physiology.org
Aside from the first week postnatal, murine heart regeneration is restricted and responses to
damage follow classic fibrotic remodeling. Recent transcriptomic analyses have suggested …

Atrial natriuretic peptide inhibits epithelial-mesenchymal transition (EMT) of bronchial epithelial cells through cGMP/PKG signaling by targeting Smad3 in a murine …

S Chu, X Zhang, Y Sun, Y Liang, J Sun… - Experimental lung …, 2019 - Taylor & Francis
Background: Atrial natriuretic peptide (ANP) inhibits TGF-β1-induced epithelial-
mesenchymal transition (EMT) in human airway cells. We aim to explore the role and …

The potential role of atrial natriuretic peptide in the effects of Angiotensin-(1–7) in a chronic atrial tachycardia canine model

J Zhao, T Liu, E Liu, G Li, L Qi… - Journal of the Renin …, 2016 - journals.sagepub.com
Objective: The objective of this article is to investigate the possible role of atrial natriuretic
peptide (ANP) in Angiotensin-(1–7)(Ang-(1–7)) signaling pathway on atrial electrical and …

Inhibition of Atrial Natriuretic Peptide Clearance Reduces Myocardial Fibrosis and Improves Cardiac Function in Diabetic Rats

N Fares, JJ Bakhos, Y Saliba, J Hajal, G Achkouty… - bioRxiv, 2024 - biorxiv.org
Background: Natriuretic peptides (NP) exert pleotropic effects through the recruitment of
cGMP-signaling pathways depending on their bioavailability which is regulated by …

Myocardial interaction of apixaban after experimental acute volume overload

C Huuskonen, M Hämäläinen… - Journal of …, 2022 - journals.sagepub.com
Objective Acute volume overload (AVO) induces early ischemia-like changes in
intramyocardial arteries. We investigated whether the Factor Xa (FXa) inhibitor apixaban …

[HTML][HTML] Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models: Regenerative cross talk between cardiac …

AJ Whitehead, AJ Engler - American Journal of Physiology-Heart …, 2021 - ncbi.nlm.nih.gov
Aside from the first week postnatal, murine heart regeneration is restricted and responses to
damage follow classic fibrotic remodeling. Recent transcriptomic analyses have suggested …

In vitro differentiation of W8B2+ human cardiac stem cells: gene expression of ionic channels and spontaneous calcium activity

O Ayad, ZR Al Sayed, S Sebille, C Magaud… - Cellular & Molecular …, 2020 - Springer
Background Human cardiac stem cells expressing the W8B2 marker (W8B2+ CSCs) were
recently identified and proposed as a new model of multipotent CSCs capable of …

ANP/NPRA inhibits epithelial-mesenchymal transition of airway by targeting Smad3 in asthma

S Chu, X Zhang, Y Sun, Y Liang, J Sun, M Lu… - International Journal of …, 2019 - Springer
Atrial natriuretic peptide (ANP) has a protective effect on allergic disorders of airway. It could
inhibit transforming growth factor beta 1 (TGF-β1)-induced epithelial-mesenchymal transition …

[PDF][PDF] TRATAMENTO CRÔNICO COM DECANOATO DE NANDROLONA INDUZ REMODELAMENTO CARDÍACO E RENAL EM RATAS, SEM MODIFICAR …

GA BRASIL - repositorio.ufes.br
Os hormônios sexuais são responsáveis pelos caracteres sexuais masculinos e femininos e
diversas ações são atribuídas a esses, como por exemplo, cardiovasculares e endócrinos …