Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2012 - pubs.rsc.org
Covering: 2010. Previous review: Nat. Prod. Rep., 2011, 28, 196 This review covers the
literature published in 2010 for marine natural products, with 895 citations (590 for the …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2004 - pubs.rsc.org
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …

The essentials of marine biotechnology

A Rotter, M Barbier, F Bertoni, AM Bones… - Frontiers In marine …, 2021 - frontiersin.org
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …

Marine sponge natural products with anticancer potential: An updated review

C Calcabrini, E Catanzaro, A Bishayee, E Turrini… - Marine drugs, 2017 - mdpi.com
Despite the huge investment into research and the significant effort and advances made in
the search for new anticancer drugs in recent decades, cancer cure and treatment continue …

Metabolomic tools for secondary metabolite discovery from marine microbial symbionts

L Macintyre, T Zhang, C Viegelmann, I Juarez Martinez… - Marine drugs, 2014 - mdpi.com
Marine invertebrate-associated symbiotic bacteria produce a plethora of novel secondary
metabolites which may be structurally unique with interesting pharmacological properties …

Bioactive compounds from marine invertebrates for potential medicines-an overview

D Datta, SN Talapatra, S Swarnakar - International Letters of Natural …, 2015 - agro.icm.edu.pl
The present review deals with the bioactive compounds of the marine non-chordates. The
potent medicinal usage of the bioactive compounds viz. steroids, terpenoids, isoprenoid and …

What tubulin drugs tell us about microtubule structure and dynamics

LA Amos - Seminars in cell & developmental biology, 2011 - Elsevier
A wide range of small molecules, including alkaloids, macrolides and peptides, bind to
tubulin and disturb microtubule assembly dynamics. Some agents inhibit assembly, others …

Quest for efficacious next-generation taxoid anticancer agents and their tumor-targeted delivery

I Ojima, X Wang, Y Jing, C Wang - Journal of natural products, 2018 - ACS Publications
Paclitaxel and docetaxel are among the most widely used chemotherapeutic drugs against
various types of cancer. However, these drugs cause undesirable side effects as well as …

Drug discovery targeting cell division proteins, microtubules and FtsZ

I Ojima, K Kumar, D Awasthi, JG Vineberg - Bioorganic & medicinal …, 2014 - Elsevier
Eukaryotic cell division or cytokinesis has been a major target for anticancer drug discovery.
After the huge success of paclitaxel and docetaxel, microtubule-stabilizing agents (MSAs) …

Tandem Macrolactone Synthesis: Total Synthesis of (−)‐Exiguolide by a Macrocyclization/Transannular Pyran Cyclization Strategy

D Mizukami, K Iio, M Oda, Y Onodera… - Angewandte Chemie …, 2022 - Wiley Online Library
Tetrahydropyran‐containing macrolactones were synthesized by integrating Meyer–
Schuster rearrangement, macrocyclic ring‐closing metathesis, and transannular oxa …