Molecular abnormalities in BTBR mice and their relevance to schizophrenia and autism spectrum disorders: an overview of transcriptomic and proteomic studies

P Kisaretova, A Tsybko, N Bondar, V Reshetnikov - Biomedicines, 2023 - mdpi.com
Animal models of psychopathologies are of exceptional interest for neurobiologists because
these models allow us to clarify molecular mechanisms underlying the pathologies. One …

Diagnostic value of circRNAs as potential biomarkers in oral squamous cell carcinoma: a meta-analysis

M Wang, L Zhang, W Ren, S Li, K Zhi, J Zheng… - Frontiers in …, 2021 - frontiersin.org
Introduction Circular RNAs (CircRNAs), an emerging non-coding RNA, have been
demonstrated to be involved in tumorigenesis, metastasis, and cancer progression, and …

[HTML][HTML] Supplementation with selenium attenuates autism-like behaviors and improves oxidative stress, inflammation and related gene expression in an autism …

H Wu, G Zhao, S Liu, Q Zhang, P Wang, Y Cao… - The Journal of Nutritional …, 2022 - Elsevier
Autism spectrum disorder (ASD) refers to a group of neurodevelopmental disorders. The
etiology and pathological mechanisms of ASD are still unknown, and its prognosis is poor …

[HTML][HTML] Alterations in microbiota-metabolism-circRNA crosstalk in autism spectrum disorder-like behaviours caused by maternal exposure to glyphosate-based …

X He, Y Yang, S Zhou, Q Wei, H Zhou, J Tao… - Ecotoxicology and …, 2024 - Elsevier
Epidemiological evidence indicates exposure to glyphosate-based herbicides (GBHs)
increases the risk for autism spectrum disorder (ASD). The gut microbiota has been found to …

[HTML][HTML] Spinal CircKcnk9 regulates chronic visceral hypersensitivity of irritable bowel syndrome

Z Chen, Y Liu, X Wu, W Lin, Z Liu, Y Huang, Y Chen… - The Journal of …, 2023 - Elsevier
Dysregulation of circular RNAs (circRNAs) has been reported to be functionally associated
with chronic pain, but it is unknown whether and how circRNAs participate in visceral …

[HTML][HTML] A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain

V Silenzi, E D'Ambra, T Santini, S D'Uva, A Setti… - Cell Reports, 2024 - cell.com
Functional studies of circular RNAs (circRNAs) began quite recently, and few data exist on
their function in vivo. Here, we have generated a knockout (KO) mouse model to study …

The secret garden of neuronal circRNAs

S Gasparini, V Licursi, C Presutti, C Mannironi - Cells, 2020 - mdpi.com
High-throughput transcriptomic profiling approaches have revealed that circular RNAs
(circRNAs) are important transcriptional gene products, identified across a broad range of …

Circular RNAs: New players involved in the regulation of cognition and cognitive diseases

X Yu, H Liu, N Chang, W Fu, Z Guo… - Frontiers in Neuroscience, 2023 - frontiersin.org
Circular RNAs (circRNAs), a type of covalently closed endogenous single-stranded RNA,
have been regarded as the byproducts of the aberrant splicing of genes without any …

Dietary lipoic acid alleviates autism-like behavior induced by acrylamide in adolescent mice: the potential involvement of the gut–brain axis

J Ye, H Fan, R Shi, G Song, X Wu, D Wang, B Xia… - Food & Function, 2024 - pubs.rsc.org
Consuming fried foods has been associated with an increased susceptibility to mental
health disorders. Nevertheless, the impact of alpha-lipoic acid (α-LA, LA) on fried food …

Circular RNA expression profiles and functional predication after restraint stress in the amygdala of rats

C Wang, Q Wang, G Xu, Z Sun, D Zhang… - Frontiers in Molecular …, 2024 - frontiersin.org
Prolonged or repeated exposure to stress elevates the risk of various psychological
diseases, many of which are characterized by central nervous system dysfunction. Recent …