This paper presents surrogate models of dissolution behavior to identify the critical input
parameters in tablet manufacturing processes. Dissolution behavior is a critical quality …

This work presents a design framework for solid drug product manufacturing processes
based on economic and quality assessment. Process alternatives were generated using a …

During the last years, regulatory bodies have demanded a more flexible and efficient
pharmaceutical production that provides qualified drugs. In order to improve the quality of …

抄録 Continuous manufacturing has become a realistic option in the pharmaceutical
industry. As such, process design becomes more complicated where this new option is …