Detecting novel ototoxins and potentiation of ototoxicity by disease settings

AB Coffin, R Boney, J Hill, C Tian, PS Steyger - Frontiers in neurology, 2021 - frontiersin.org
Over 100 drugs and chemicals are associated with permanent hearing loss, tinnitus, and
vestibular deficits, collectively known as ototoxicity. The ototoxic potential of drugs is rarely …

The sound world of zebrafish: A critical review of hearing assessment

AN Popper, JA Sisneros - Zebrafish, 2022 - liebertpub.com
Zebrafish, like all fish species, use sound to learn about their environment. Thus, human-
generated (anthropogenic) sound added to the environment has the potential to disrupt the …

Boat noise affects meagre (Argyrosomus regius) hearing and vocal behaviour

M Vieira, M Beauchaud, MCP Amorim… - Marine Pollution …, 2021 - Elsevier
Aquatic noise has increased in last decades imposing new constraints on aquatic animals'
acoustic communication. Meagre (Argyrosomus regius) produce loud choruses during the …

Noise-induced hearing loss in zebrafish: investigating structural and functional inner ear damage and recovery

L Breitzler, IH Lau, PJ Fonseca, RO Vasconcelos - Hearing research, 2020 - Elsevier
Exposure to continuous moderate noise levels is known to impair the auditory system
leading to Noise-Induced Hearing Loss (NIHL) in animals including humans. The …

Characterizing sources of variability in zebrafish embryo screening protocols

JT Hamm, P Ceger, D Allen, M Stout, EA Maull… - Altex, 2018 - pmc.ncbi.nlm.nih.gov
There is a need for fast, efficient, and cost-effective hazard identification and characterization
of chemical hazards. This need is generating increased interest in the use of zebrafish …

Noise-induced hearing loss in zebrafish model: Characterization of tonotopy and sex-based differences

E Han, DH Lee, S Park, YC Rah, HC Park, JW Choi… - Hearing research, 2022 - Elsevier
Hearing loss caused by frequent and persistent exposure to loud noise is one of the most
common diseases in modern society. Many studies have demonstrated the characteristics of …

Noise-induced hearing loss correlates with inner ear hair cell decrease in larval zebrafish

RA Lara, L Breitzler, IH Lau… - Journal of …, 2022 - journals.biologists.com
Anthropogenic noise can be hazardous for the auditory system and wellbeing of animals,
including humans. However, very limited information is known on how this global …

Naringin attenuates cisplatin‐and aminoglycoside‐induced hair cell injury in the zebrafish lateral line via multiple pathways

M Li, J Liu, D Liu, X Duan, Q Zhang… - Journal of cellular …, 2021 - Wiley Online Library
Exposure to ototoxic drugs is a significant cause of hearing loss that affects about 30
thousand children with potentially serious physical, social and psychological dysfunctions …

Characterization of the natural soundscape of zebrafish and comparison with the captive noise conditions

RA Lara, RO Vasconcelos - Zebrafish, 2019 - liebertpub.com
Zebrafish is a well-established model organism in hearing research. Although the acoustic
environment is known to shape the structure and sensitivity of auditory systems, there is no …

[HTML][HTML] Localization of Piezo 1 and Piezo 2 in Lateral Line System and Inner Ear of Zebrafish (Danio rerio)

M Aragona, K Mhalhel, L Pansera… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Piezo proteins have been identified as mechanosensitive ion channels involved in
mechanotransduction. Several ion channel dysfunctions may be associated with diseases …