Adequate oxygen delivery to a tissue depends on sufficient oxygen content in arterial blood
and blood flow to the tissue. Oximetry is a technique for the assessment of blood …

Multimodal monitoring has become particularly common in the study of human brain
function. In this context, combined, synchronous measurements of functional near-infrared …

Despite improvements in the mortality rates of preterm infants, rates of germinal matrix
intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25% in …

The cardiovascular care of critically ill preterm infants, particularly around the periviable
period, remains a significant challenge in the neonatal intensive care unit for a multitude of …

Significance: Multi-laboratory initiatives are essential in performance assessment and
standardization—crucial for bringing biophotonics to mature clinical use—to establish …

Cerebrovascular pressure autoregulation promotes stable cerebral blood flow (CBF) across
a range of arterial blood pressures. Cerebral autoregulation (CA) is a developmental …

Functional near-infrared spectroscopy (fNIRS) is a method of monitoring brain oxygenation.
This technique investigates hemodynamic changes in the cerebral cortex. fNIRS is widely …

Abstract Near-infrared spectroscopy (NIRS)-based monitoring of regional tissue oxygenation
(rSO2) is becoming more commonplace in the neonatal intensive care unit (NICU). While …

Background: General anesthesia during infancy is associated with neurocognitive
abnormalities. Potential mechanisms include anesthetic neurotoxicity, surgical disease, and …

Safeguarding cerebral function is of major importance during pediatric anesthesia.
Premature, ex‐premature, and full‐term neonates can be vulnerable to physiological …