[HTML][HTML] Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects

R Pereira, AMS Silva, D Ribeiro, VLM Silva… - European Journal of …, 2023 - Elsevier
Chalcones are bioactive molecules of natural and synthetic sources, whose
physicochemical properties, reactivity, and biological activities are well-known among the …

Significance of chalcone scaffolds in medicinal chemistry

R Mazumder, Ichudaule, A Ghosh, S Deb… - Topics in Current …, 2024 - Springer
Chalcone is a simple naturally occurring α, β-unsaturated ketone with biological importance,
which can also be easily synthesized in laboratories by reaction between two aromatic …

Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies

M Tapera, H Kekeçmuhammed, E Sarıpınar… - Journal of Molecular …, 2023 - Elsevier
In the present work, a series of compounds containing imidazole and hydrazone structural
frameworks were synthesized and characterized using various spectral techniques …

Antibiofilm and Anti-Quorum-Sensing Activities of Novel Pyrazole and Pyrazolo[1,5-a]pyrimidine Derivatives as Carbonic Anhydrase I and II Inhibitors: Design …

A Ragab, SA Fouad, YA Ammar, DS Aboul-Magd… - Antibiotics, 2023 - mdpi.com
Nowadays, searching for new anti-infective agents with diverse mechanisms of action has
become necessary. In this study, 16 pyrazole and pyrazolo [1, 5-a] pyrimidine derivatives …

Ultrasound promoted stereoselective synthesis of 2, 3-dihydrobenzofuran appended chalcones at ambient temperature

VA Adole, BS Jagdale, TB Pawar, AA Sagane - South african journal of …, 2020 - ajol.info
In the present investigation, an ultrasound promoted the synthesis of a series of (E)-3-(2, 3-
dihydrobenzofuran 5-yl)-1-(aryl) prop-2-en-1-one derivatives from 2, 3-dihydrobenzofuran-5 …

Biologically active phthalocyanine metal complexes: Preparation, evaluation of α‐glycosidase and anticholinesterase enzyme inhibition activities, and molecular …

E Güzel, ÜM Koçyiğit, P Taslimi… - … of Biochemical and …, 2021 - Wiley Online Library
In this study, preparation, as well as investigation of α‐glycosidase and cholinesterase
(ChE) enzyme inhibition activities of furan‐2‐ylmethoxy‐substituted compounds 1–7, are …

Chalcones, a privileged scaffold: highly versatile molecules in [4+ 2] cycloadditions

S Mastachi‐Loza… - Chemistry–An Asian …, 2022 - Wiley Online Library
Chalcones are aromatic ketones found in nature as the central core of many biological
compounds. They have a wide range of biological activity and are biogenetic precursors of …

Synthesis, characterization, and biological studies of chalcone derivatives containing Schiff bases: Synthetic derivatives for the treatment of epilepsy and Alzheimer's …

ÜM Koçyiğit, H Gezegen, P Taslimi - Archiv der pharmazie, 2020 - Wiley Online Library
In this study, first, Schiff base‐containing chalcone derivatives were synthesized. The human
carbonic anhydrase (hCA) isoenzymes I and II were then purified from human erythrocytes …

Chalcones with potential antibacterial and antibiofilm activities against periodontopathogenic bacteria

AAC Satokata, JH Souza, LLO Silva, MB Santiago… - Anaerobe, 2022 - Elsevier
Objectives Periodontitis is a pathology resulting from complex interaction of microorganisms
in the dental biofilm with the host's immune system. Increased use of antibiotics associated …

Arylated quinoline and tetrahydroquinolines: Synthesis, characterization and their metabolic enzyme inhibitory and antimicrobial activities

ÜM Koçyiğit, S Ökten, O Cakmak, G Burhan… - …, 2022 - Wiley Online Library
The aims of this study are to synthesize and characterize some new phenyl quinoline
derivatives and to determine the activities of them and the recently prepared substituted …