Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology

LGN de Almeida, H Thode, Y Eslambolchi… - Pharmacological …, 2022 - ASPET
The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Ulcerative colitis in adults: A review

B Gros, GG Kaplan - Jama, 2023 - jamanetwork.com
Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …

Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery

J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …

Treatment of inflammatory bowel disease: a comprehensive review

Z Cai, S Wang, J Li - Frontiers in medicine, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), as a global disease, has attracted much research
interest. Constant research has led to a better understanding of the disease condition and …

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global …

R Wang, Z Li, S Liu, D Zhang - BMJ open, 2023 - bmjopen.bmj.com
Objectives We aimed to provide the most updated estimates on the global burden of
inflammatory bowel disease (IBD) to improve management strategies. Design We extracted …

Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis

Z Wu, S Huang, T Li, N Li, D Han, B Zhang, ZZ Xu… - Microbiome, 2021 - Springer
Background Alteration of the gut microbiota may contribute to the development of
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …

[HTML][HTML] Twenty-first century trends in the global epidemiology of pediatric-onset inflammatory bowel disease: systematic review

ME Kuenzig, SG Fung, L Marderfeld, JWY Mak… - Gastroenterology, 2022 - Elsevier
Background & aims The incidence of inflammatory bowel disease (IBD) is increasing
internationally, particularly in nations with historically low rates. Previous reports of the …

The gut microbiota in inflammatory bowel disease

P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang… - Frontiers in cellular and …, 2022 - frontiersin.org
Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

[HTML][HTML] Global incidence of acute pancreatitis is increasing over time: a systematic review and meta-analysis

JP Iannuzzi, JA King, JH Leong, J Quan, JW Windsor… - Gastroenterology, 2022 - Elsevier
Background & Aims Acute pancreatitis is a common disease with significant associated
morbidity and mortality. We performed a systematic review and meta-analysis of population …

Dietary fibre in gastrointestinal health and disease

SK Gill, M Rossi, B Bajka, K Whelan - Nature Reviews Gastroenterology …, 2021 - nature.com
Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …