Tauroursodeoxycholic acid (TUDCA) is a naturally occurring hydrophilic bile acid that has
been used for centuries in Chinese medicine. Chemically, TUDCA is a taurine conjugate of …

Brown trout Salmo trutta is endemic to Europe, western Asia and north‐western Africa; it is a
prominent member of freshwater and coastal marine fish faunas. The species shows two …

RNA and DNA modifications occur in eukaryotes and prokaryotes, as well as in their viruses,
and serve a wide range of functions, from gene regulation to nucleic acid protection …

Diabetic nephropathy (DN) is still one of the leading causes of end-stage renal disease
despite the emergence of different therapies to counter the metabolic, hemodynamic and …

Three novel series of triazolophthalazine derivatives bearing hydrazone moiety were
designed, synthesized, and evaluated for their anticancer activity against four human cancer …

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder, which is
caused by mutations in the PKD1 and PKD2 genes, characterizing by progressive growth of …

Epigenetics is currently one of the fastest-growing fields in the sciences. Epigenetic
information not only controls DNA expression but links genetic factors with the …

Cancer is an important factor threatening human life and health; in recent years, its morbidity
and mortality remain high and demosntrate an upward trend. It is of great significance to …

Iron deficiency is a common micronutrient deficiency associated with metabolic changes in
the levels of iron regulatory proteins, hepcidin and ferroportin. Studies have associated …

Nephropathy is one of the most frequent complications of chronic diabetes. The main reason
for nephropathy despite being hyperglycemia, but it progresses even after good glycemic …