Bone organoids: recent advances and Future challenges

D Zhao, Q Saiding, Y Li, Y Tang… - Advanced Healthcare …, 2024 - Wiley Online Library
Bone defects stemming from tumorous growths, traumatic events, and diverse conditions
present a profound conundrum in clinical practice and research. While bone has the …

Dynamic hydrogels with viscoelasticity and tunable stiffness for the regulation of cell behavior and fate

Y Zhang, Z Wang, Q Sun, Q Li, S Li, X Li - Materials, 2023 - mdpi.com
The extracellular matrix (ECM) of natural cells typically exhibits dynamic mechanical
properties (viscoelasticity and dynamic stiffness). The viscoelasticity and dynamic stiffness of …

Supramolecular chitin-based hydrogels with self-adapting and fast-degradation properties for enhancing wound healing

W Shi, D Zhang, L Han, W Shao, Q Liu, B Song… - Carbohydrate …, 2024 - Elsevier
Due to the features of high porosity, high water content, and tunable viscoelasticity,
hydrogels have attracted numerous attentions in the promotion of wound closure. However …

[HTML][HTML] A mesenchymal stem cell-derived nanovesicle-biopotentiated bovine serum albumin-bridged gelatin hydrogel for enhanced diabetic wound therapy

Y Wu, M Su, S Zhang, L Xiao, Y Xiao, M Zhang, Y Bei… - Materials & Design, 2023 - Elsevier
The application of gelatin hydrogels is hampered by their poor mechanical properties, which
are unfavorable for debridement and diabetic wound healing. Herein, bovine serum albumin …

Photocuring and gelatin-based antibacterial hydrogel for skin care

M Wang, F Yang, H Luo, Y Jiang, K Zhuang… - …, 2023 - ACS Publications
The development of moisturizing, antibacterial, and biocompatible multifunctional hydrogels
is essential to protect skin and promote skin defects recovery. Gelatin has admired potential …

Lyophilized platelet-rich fibrin exudate-loaded carboxymethyl chitosan/GelMA hydrogel for efficient bone defect repair

S Gan, Z Zheng, M Zhang, L Long… - … Applied Materials & …, 2023 - ACS Publications
Platelet-rich fibrin (PRF) is an autologous growth factor carrier that promotes bone tissue
regeneration, but its effectiveness is restrained by poor storage capabilities, uncontrollable …

pH‐and temperature‐responsive hydrogels based on tertiary amine‐modified polypeptides for stimuli‐responsive drug delivery

Z Lin, J Ding, X Chen, C He - Chemistry–An Asian Journal, 2023 - Wiley Online Library
Abstract pH‐and temperature‐responsive hydrogels have attracted considerable attention
due to their responsiveness to dual physiologically‐relevant stimuli. In this study, we …

Coacervation‐Mediated Cytocompatible Formation of Supramolecular Hydrogels with Self‐Evolving Macropores for 3D Multicellular Spheroid Culture

X Yang, B Yang, Y Deng, X Xie, Y Qi, G Yan… - Advanced …, 2023 - Wiley Online Library
Coacervation driven liquid–liquid phase separation of biopolymers has aroused
considerable attention for diverse applications, especially for the construction of …

Injectable decellularized extracellular matrix hydrogel with cell-adaptable supramolecular network enhances cartilage regeneration by regulating inflammation and …

W Dai, X Gong, C Wang, P Liu, W Shi, J Cheng… - Chemical Engineering …, 2024 - Elsevier
Osteoarthritis, characterized by progressive loss of cartilage, affects millions of people
worldwide and clinically lacks effective treatments. Herein, we present an injectable …

Advances in the application of extracellular vesicles derived from three-dimensional culture of stem cells

W Chen, P Wu, C Jin, Y Chen, C Li, H Qian - Journal of …, 2024 - Springer
Stem cells (SCs) have been used therapeutically for decades, yet their applications are
limited by factors such as the risk of immune rejection and potential tumorigenicity …