Toxic effects and mechanisms of polybrominated diphenyl ethers

J Xue, Q Xiao, M Zhang, D Li, X Wang - International Journal of Molecular …, 2023 - mdpi.com
Polybrominated diphenyl ethers (PBDEs) are a group of flame retardants used in plastics,
textiles, polyurethane foam, and other materials. They contain two halogenated aromatic …

[HTML][HTML] The effects of brominated flame retardants (BFRs) on pro-atherosclerosis mechanisms

HD Wu, LW Yang, DY Deng, RN Jiang, ZK Song… - Ecotoxicology and …, 2023 - Elsevier
Brominated flame-retardants (BFRs) are environmental endocrine disruptors, comprising
several pollutants, which potentially affect the endocrine system and cause dysfunction and …

[HTML][HTML] Metabolomics and transcriptomics reveal defense mechanism of rice (Oryza sativa) grains under stress of 2, 2′, 4, 4′-tetrabromodiphenyl ether

J Chen, XC Le, L Zhu - Environment international, 2019 - Elsevier
Abstract 2, 2′, 4, 4′-Tetrabromodiphenyl ether (BDE-47), a predominant polybrominated
diphenyl ether (PBDE), has received extensive attention for its potential environmental …

Toxicity of tetrabromobisphenol A and its derivative in the mouse liver following oral exposure at environmentally relevant levels

L Yao, Y Wang, J Shi, Y Liu, H Guo… - Environmental …, 2021 - ACS Publications
As typical brominated flame retardants (BFRs), tetrabromobisphenol A (TBBPA) and its
derivative TBBPA-bis (2, 3-dibromopropyl ether)(TBBPA-BDBPE) are ubiquitous in various …

[HTML][HTML] Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive …

L Dong, P Li, K Yang, L Liu, H Gao, G Zhou, Q Zhao… - Theranostics, 2020 - ncbi.nlm.nih.gov
Polybrominated diphenyl ethers (PBDEs)-induced neurotoxicity is closely associated with
mitochondrial abnormalities. Mitochondrial fusion and fission dynamics are required for the …

BDE-47 induced apoptosis in zebrafish embryos through mitochondrial ROS-mediated JNK signaling

J Zhuang, Z Pan, F Hong, C Zhu, N Wu, G Chang… - Chemosphere, 2020 - Elsevier
Abstract 2, 2, 4, 4-tetrabromodiphenyl ether (BDE-47) has received considerable attention
because of its high detection level in biological samples and potential developmental …

Exposure to persistent organic pollutants (POPs) and their relationship to hepatic fat and insulin insensitivity among Asian Indian immigrants in the United States

MA La Merrill, CL Johnson, MT Smith… - … science & technology, 2019 - ACS Publications
Persistent organic pollutants (POPs), such as dichlorodiphenyltrichloroethane (DDT) and
other organochlorine compounds, are abundant in the environment and in foodstuffs from …

Neonatal exposure to BPA, BDE-99, and PCB produces persistent changes in hepatic transcriptome associated with gut dysbiosis in adult mouse livers

JJ Lim, M Dutta, JL Dempsey, HJ Lehmler… - Toxicological …, 2021 - academic.oup.com
Recent evidence suggests that complex diseases can result from early life exposure to
environmental toxicants. Polybrominated diphenyl ethers (PBDEs), and polychlorinated …

Associations between polybrominated diphenyl ethers (PBDEs) levels in adipose tissues and blood lipids in women of Shantou, China

Q Zhang, J Peng, A Huang, S Zheng, X Shi, B Li… - Environmental …, 2022 - Elsevier
Animal studies have indicated that exposure to polybrominated diphenyl ethers (PBDEs)
during development can permanently affect blood/liver lipid balance. However, no …

[HTML][HTML] Developmental exposure to indoor flame retardants and hypothalamic molecular signatures: Sex-dependent reprogramming of lipid homeostasis

EV Kozlova, ME Denys, J Benedum… - Frontiers in …, 2022 - frontiersin.org
Polybrominated diphenyl ethers (PBDEs) are a class of flame-retardant organohalogen
pollutants that act as endocrine/neuroendocrine disrupting chemicals (EDCs). In humans …