Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Obesity and bone health: a complex relationship

A Piñar-Gutierrez, C García-Fontana… - International journal of …, 2022 - mdpi.com
Recent scientific evidence has shown an increased risk of fractures in patients with obesity,
especially in those with a higher visceral adipose tissue content. This contradicts the old …

BMI and BMD: the potential interplay between obesity and bone fragility

A Palermo, D Tuccinardi, G Defeudis… - International journal of …, 2016 - mdpi.com
Recent evidence demonstrating an increased fracture risk among obese individuals
suggests that adipose tissue may negatively impact bone health, challenging the traditional …

Treatment of functional hypogonadism besides pharmacological substitution

G Corona, G Rastrelli, A Morelli… - The world journal of …, 2019 - pmc.ncbi.nlm.nih.gov
A dichotomic distinction between “organic” and “functional” hypogonadism is emerging. The
former is an irreversible condition due to congenital or “acquired”“organic” damage of the …

[HTML][HTML] Vitamin D status and weight loss: a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials

SR Mallard, AS Howe, LA Houghton - The American journal of clinical …, 2016 - Elsevier
Background: Obesity is associated with lower concentrations of serum 25-hydroxyvitamin D;
however, uncertainty exists as to the direction of causation. To date, meta-analyses of …

[HTML][HTML] Rapid weight loss vs. slow weight loss: which is more effective on body composition and metabolic risk factors?

D Ashtary-Larky, M Ghanavati… - … of endocrinology and …, 2017 - ncbi.nlm.nih.gov
Background Achieving weight loss (WL) in a short time regardless of its consequences has
always been the focus of many obese and overweight people. In this study, anthropometric …

Leptin as a biomarker of stress: a systematic review and meta-analysis

JB Bouillon-Minois, M Trousselard, D Thivel… - Nutrients, 2021 - mdpi.com
Background: Leptin is a satiety hormone mainly produced by white adipose tissue.
Decreasing levels have been described following acute stress. Objective: To conduct a …

The effects of weight loss approaches on bone mineral density in adults: a systematic review and meta-analysis of randomized controlled trials

S Soltani, GR Hunter, A Kazemi… - Osteoporosis International, 2016 - Springer
We assessed the impact of weight loss strategies including calorie restriction and exercise
training on BMD in adults using a systematic review of randomized controlled trials. Weight …

Fat as a Friend or Foe of the Bone

E Gruneisen, R Kremer, G Duque - Current Osteoporosis Reports, 2024 - Springer
Abstract Purpose of Review The objective of this review is to summarize the literature on the
prevalence and diagnosis of obesity and its metabolic profile, including bone metabolism …

Bone loss at the distal femur and proximal tibia in persons with spinal cord injury: imaging approaches, risk of fracture, and potential treatment options

CM Cirnigliaro, MJ Myslinski, MF La Fountaine… - Osteoporosis …, 2017 - Springer
Persons with spinal cord injury (SCI) undergo immediate unloading of the skeleton and, as a
result, have severe bone loss below the level of lesion associated with increased risk of long …