The review by Christianson, published in 2017 on the twentieth anniversary of the
emergence of the field, summarizes the foundational discoveries and key advances in …

Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

Proteins are molecular machines composed of complex, highly connected amino acid
networks. Their functional optimization requires the reorganization of these intramolecular …

Terpene synthases (TS) catalyze complex reactions to produce a diverse array of terpene
skeletons from linear isoprenyl diphosphates. Patchoulol synthase (PTS) from Pogostemon …

How do proteins evolve? How do changes in sequence mediate changes in protein
structure, and in turn in function? This question has multiple angles, ranging from …

Covering: up to the beginning of 2023 Many animals release volatile or semi-volatile
terpenes as semiochemicals in intra-and inter-specific interactions. Terpenes are important …

Terpenoids form the most diversified class of natural products, which have gained
application in the pharmaceutical, food, transportation, and fine and bulk chemical …

Engineering sesquiterpene synthases to form predefined alternative products is a major
challenge due to their diversity in cyclization mechanisms and our limited understanding of …

Background Metabolic engineering of cyanobacteria has enabled photosynthetic conversion
of CO 2 to value-added chemicals as bio-solar cell factories. However, the production levels …

Insects use diverse arrays of small molecules such as metabolites of the large class of
terpenes for intra-and inter-specific communication and defense. These molecules are …