Accessing the human trophoblast stem cell state from pluripotent and somatic cells

RM Karvas, L David, TW Theunissen - Cellular and Molecular Life …, 2022 - Springer
Trophoblasts are specialized epithelial cells that perform critical functions during blastocyst
implantation and mediate maternal–fetal communication during pregnancy. However, our …

KLF7 is a general inducer of human pluripotency

M Arboit, I Zorzan, M Pellegrini, P Martini, E Carbognin… - bioRxiv, 2023 - biorxiv.org
Pluripotency is the capacity to give rise to all differentiated cells of the body and the germ
line and is governed by a self-reinforcing network of transcription factors. The forced …