Huntington's disease (HD) is characterized by defective oligodendroglial differentiation and
white matter disease. Here, we investigate the role of oligodendrocyte progenitor cell (OPC) …

Since its first discovery in the late 90s, Wnt canonical signaling has been demonstrated to
affect a large variety of neural developmental processes, including, but not limited to …

Several studies showed the efficacy of Lycium barbarum polysaccharide (LBP) in diabetic
animals and patients with type 2 diabetes mellitus (T2DM). However, the mechanism of LBP …

To gain further insight into chromatin‐mediated regulation of mammalian sex determination,
we analyzed the role of the CHARGE syndrome‐associated proteins FAM172A and CHD7 …

Acute renal injury (ARI) is a life‑threatening condition and a main contributor to end‑stage
renal disease, which is mainly caused by ischemia‑reperfusion (I/R). miR‑106b‑5p is a …

Wnt signaling is essential during animal development and regeneration, but also plays an
important role in diseases such as cancer and diabetes. The canonical Wnt signaling …

Introduction Non-coding genetic variation at TCF7L2 is the strongest genetic determinant of
type 2 diabetes (T2D) risk in humans. TCF7L2 encodes a transcription factor mediating the …

Hetian sheep have a long history and a wide distribution. They are renowned for their carpet-
grade wool, which makes them a valuable genetic resource in China. The survey revealed …

Colorectal cancer (CRC) is the third most prevalent cancer in the world for both men and
women. Overall, rates of CRC are on a steady decline, yet rates in young adults have seen a …

Huntington's disease (HD) is characterized by defective oligodendroglial differentiation and
white matter disease. Here, we investigated the role of glial progenitor cell (GPC) …