Cutaneous squamous cell carcinoma (cSCC), a non-melanoma skin cancer, is a
keratinocyte carcinoma representing one of the most common cancers with an increasing …

Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

Colorectal cancer (CRC) is a serious disease that affects millions of people throughout the
world, despite considerable advances in therapy. The formation of colorectal adenomas and …

The transcription factor nuclear factor kappa B (NF-κB) has attracted increasing attention in
the field of cancer research from last few decades. Aberrant activation of this transcription …

The recent elucidation of the genomic landscape of head and neck squamous cell
carcinoma (HNSCC) has provided a unique opportunity to develop selective cancer …

Constitutive activation of proinflammatory transcription factors such as STAT3 and NF-κB
plays a pivotal role in the proliferation and survival of squamous cell carcinoma of the head …

Protein kinase CK2, a protein serine/threonine kinase, plays a global role in activities related
to cell growth, cell death, and cell survival. CK2 has a large number of potential substrates …

The nuclear factor-κB (NF-κB) pathway is one of the most important cellular signal
transduction pathways involved in both physiologic processes and disease conditions. It …

Abstract Extracellular sulfatase-2 (Sulf-2) influences receptor–ligand binding and
subsequent signaling by chemokines and growth factors, yet Sulf-2 remains unexplored in …

Laryngopharyngeal reflux, a variant of gastroesophageal reflux disease, has been
considered a risk factor in the development of hypopharyngeal cancer. Bile acids are …