In parallel with the development of tissue-clearing methods, over the last decade, light sheet
fluorescence microscopy has contributed to major advances in various fields, such as cell …

Mass Spectrometry Imaging (MSI) is a technique used to identify the spatial distribution of
molecules in tissues. An MSI experiment results in large amounts of high dimensional data …

Here, we summarize the literature relevant to recent advances in three‐dimensional (3D)
histopathology in relation to clinical oncology, highlighting serial sectioning, tissue clearing …

Targeted (nano-) drug delivery is essential for treating respiratory diseases, which are often
confined to distinct lung regions. However, spatio-temporal profiling of drugs or …

Organ-specific lymphatics are essential for the maintenance of healthy organ function and
lymphatic dysfunction can lead to the development of various diseases. However, the …

Extracellular matrix (ECM) organization influences cancer development and progression. It
modulates the invasion of cancer cells and can hinder the access of immune cells to cancer …

Visualizing the whole vascular network system is crucial for understanding the pathogenesis
of specific diseases and devising targeted therapeutic interventions. Although the …

Esophageal squamous cell carcinoma (ESCC) is a common malignancy, characterized by a
multistep pathogenic process regulated spatiotemporally within the esophageal epithelial …

Introduction The development of next-generation tissue-engineered medical devices such
as tissue-engineered vascular grafts (TEVGs) is a leading trend in translational medicine …

Comprehensive visualization and accurate extraction of tumor vasculature are essential to
study the nature of glioma. Nowadays, tissue clearing technology enables 3D visualization …