Transition metals and virulence in bacteria

LD Palmer, EP Skaar - Annual review of genetics, 2016 - annualreviews.org
Transition metals are required trace elements for all forms of life. Due to their unique
inorganic and redox properties, transition metals serve as cofactors for enzymes and other …

TonB-dependent transporters: regulation, structure, and function

N Noinaj, M Guillier, TJ Barnard… - Annual review of …, 2010 - annualreviews.org
TonB-dependent transporters (TBDTs) are bacterial outer membrane proteins that bind and
transport ferric chelates, called siderophores, as well as vitamin B12, nickel complexes, and …

The role of iron and siderophores in infection, and the development of siderophore antibiotics

MGP Page - Clinical Infectious Diseases, 2019 - academic.oup.com
Iron is an essential nutrient for bacterial growth, replication, and metabolism. Humans store
iron bound to various proteins such as hemoglobin, haptoglobin, transferrin, ferritin, and …

[HTML][HTML] Siderophores: Importance in bacterial pathogenesis and applications in medicine and industry

B Khasheii, P Mahmoodi, A Mohammadzadeh - Microbiological Research, 2021 - Elsevier
Iron is an essential element for all microorganisms. Siderophores are low-weight, high-
affinity iron chelating molecules produced in response to iron deficiency by Gram-positive …

[图书][B] Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 6-10)

KM Kadish, R Guilard, KM Smith - 2010 - books.google.com
This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

Microbial iron acquisition: marine and terrestrial siderophores

M Sandy, A Butler - Chemical reviews, 2009 - ACS Publications
The vast majority of bacteria require iron for growth. 1, 2 Iron is an essential element
required for key biological processes, including amino acid synthesis, oxygen transport …

Shared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humans

M Caza, JW Kronstad - Frontiers in cellular and infection microbiology, 2013 - frontiersin.org
Iron is the most abundant transition metal in the human body and its bioavailability is
stringently controlled. In particular, iron is tightly bound to host proteins such as transferrin to …

Mycobacteria, metals, and the macrophage

O Neyrolles, F Wolschendorf, A Mitra… - Immunological …, 2015 - Wiley Online Library
Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host
macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation …

Bacterial iron detoxification at the molecular level

JM Bradley, DA Svistunenko, MT Wilson… - Journal of Biological …, 2020 - ASBMB
Iron is an essential micronutrient, and, in the case of bacteria, its availability is commonly a
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …

Sequestration and scavenging of iron in infection

NL Parrow, RE Fleming, MF Minnick - Infection and immunity, 2013 - Am Soc Microbiol
The proliferative capability of many invasive pathogens is limited by the bioavailability of
iron. Pathogens have thus developed strategies to obtain iron from their host organisms. In …