A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes

S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

The interplay between exosomes and autophagy–partners in crime

J Xu, R Camfield, SM Gorski - Journal of cell science, 2018 - journals.biologists.com
The eukaryotic endomembrane system is a complex series of interconnected membranous
organelles that play important roles in responding to stress and maintaining cell …

KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a

L Song, S Tang, X Han, Z Jiang, L Dong, C Liu… - Nature …, 2019 - nature.com
Exosomes are nanosized membrane vesicles released from cells after fusion of
multivesicular bodies (MVBs) with the plasma membrane (PM) and play important roles in …

Synergies in exosomes and autophagy pathways for cellular homeostasis and metastasis of tumor cells

L Salimi, A Akbari, N Jabbari, B Mojarad, A Vahhabi… - Cell & Bioscience, 2020 - Springer
Background Eukaryotic cells demonstrate two tightly linked vesicular transport systems,
comprising intracellular vesicle transport and extracellular vesicle transport system …

[HTML][HTML] Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches

B Jahangiri, AK Saei, PO Obi, N Asghari… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Exosomal release pathway and autophagy together maintain homeostasis and survival of
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …

Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management

RJ Ellis, MJ Marquine, M Kaul, JA Fields… - Nature Reviews …, 2023 - nature.com
People living with HIV are affected by the chronic consequences of neurocognitive
impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve …

Human immunodeficiency virus type 1 gp120 and Tat induce mitochondrial fragmentation and incomplete mitophagy in human neurons

C Teodorof-Diedrich, SA Spector - Journal of virology, 2018 - Am Soc Microbiol
ABSTRACT HIV enters the central nervous system (CNS) during the early stages of infection
and can cause neurological dysfunction, including neurodegeneration and neurocognitive …

[HTML][HTML] Seminal exosomes–an important biological marker for various disorders and syndrome in human reproduction

AS Vickram, PS Srikumar, S Srinivasan… - Saudi journal of …, 2021 - Elsevier
Background Exosomes are nano-sized membrane vesicles, secreted by different types of
cells into the body's biological fluids. They are found in abundance in semen as compared to …

Autophagy, EVs, and infections: a perfect question for a perfect time

ML Pleet, H Branscome, C DeMarino… - Frontiers in cellular …, 2018 - frontiersin.org
Autophagy, a highly conserved process, serves to maintain cellular homeostasis in
response to an extensive variety of internal and external stimuli. The classic, or canonical …

Exosomal miR-9 released from HIV tat stimulated astrocytes mediates microglial migration

L Yang, F Niu, H Yao, K Liao, X Chen, Y Kook… - Journal of Neuroimmune …, 2018 - Springer
Chronic neuroinflammation still remains a common underlying feature of HIV-infected
patients on combined anti-retroviral therapy (cART). Previous studies have reported that …