Genetics of diabetes mellitus and diabetes complications

JB Cole, JC Florez - Nature reviews nephrology, 2020 - nature.com
Diabetes is one of the fastest growing diseases worldwide, projected to affect 693 million
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …

[HTML][HTML] Biomarkers in diabetic retinopathy

AJ Jenkins, MV Joglekar, AA Hardikar… - The review of diabetic …, 2015 - ncbi.nlm.nih.gov
There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …

Adaptive selection at G6PD and disparities in diabetes complications

JH Breeyear, JN Hellwege, PH Schroeder, JS House… - Nature Medicine, 2024 - nature.com
Diabetes complications occur at higher rates in individuals of African ancestry. Glucose-6-
phosphate dehydrogenase deficiency (G6PDdef), common in some African populations …

Imaging and biomarkers in diabetic macular edema and diabetic retinopathy

CC Kwan, AA Fawzi - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR) is the leading cause of acquired
vision loss in adults across the globe. Early identification and treatment of patients with DR is …

Genetics of diabetes-associated microvascular complications

V Lyssenko, A Vaag - Diabetologia, 2023 - Springer
Diabetes is associated with excess morbidity and mortality due to both micro-and
macrovascular complications, as well as a range of non-classical comorbidities. Diabetes …

Progress in genetics of type 2 diabetes and diabetic complications

N Shojima, T Yamauchi - Journal of Diabetes Investigation, 2023 - Wiley Online Library
Type 2 diabetes results from a complex interaction between genetic and environmental
factors. Precision medicine for type 2 diabetes using genetic data is expected to predict the …

Genetics of diabetic retinopathy, a leading cause of irreversible blindness in the industrialized world

AD Bhatwadekar, A Shughoury, A Belamkar, TA Ciulla - Genes, 2021 - mdpi.com
Diabetic retinopathy (DR) is a chronic complication of diabetes and a leading cause of
blindness in the industrialized world. Traditional risk factors, such as glycemic control and …

Association of obesity and risk of diabetic retinopathy in diabetes patients: a meta-analysis of prospective cohort studies

W Zhu, Y Wu, YF Meng, Q Xing, JJ Tao, J Lu - Medicine, 2018 - journals.lww.com
Background: Diabetic retinopathy (DR) was considered to be a common complication of
diabetes. The purpose of the current study was to investigate the potential association …

Diabetic retinopathy: An epidemic at home and around the world

R Raman, L Gella, S Srinivasan… - Indian journal of …, 2016 - journals.lww.com
Prevention of blindness due to diabetic retinopathy (DR) requires effective screening
strategies, for which eye care providers need to know the magnitude of the burden and the …

Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases

SK Wang, S Nair, R Li, K Kraft, A Pampari, A Patel… - Cell genomics, 2022 - cell.com
Genome-wide association studies (GWASs) of eye disorders have identified hundreds of
genetic variants associated with ocular disease. However, the vast majority of these variants …