Pharmacologic activities of phytosteroids in inflammatory diseases: mechanism of action and therapeutic potentials

R Marahatha, K Gyawali, K Sharma… - Phytotherapy …, 2021 - Wiley Online Library
Natural products and their derivatives are known to be useful for treating numerous diseases
since ancient times. Because of their high therapeutic potentials, the use of different …

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction …

HMA Khalil, HA Eliwa, RA El-Shiekh… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Ashwagandha (ASH) is one of the medicinal plants used
in traditional Indian, Ayurvedic, and Unani medicines for their broad range of …

[PDF][PDF] Medicinal Plants with Potent Anti-inflammatory and Anti-arthritic Properties found in Eastern Parts of the Himalaya: An Ethnomedicinal Review.

B Banik, S Das, MK Das - Pharmacognosy Reviews, 2020 - pdfs.semanticscholar.org
Since ancient times, medicinal plants performing a very essential role as a source of
medicine and their medicinal properties have been well documented in the various …

Neuroprotective effects of Withania somnifera in the SH-SY5Y Parkinson cell model

J Wongtrakul, T Thongtan, B Kumrapich, C Saisawang… - Heliyon, 2021 - cell.com
Parkinson's disease is the most frequent neurodegenerative motor disorder. The clinical
syndrome and pathology involve motor disturbance and the degeneration of dopaminergic …

AMF enhance secondary metabolite production in ashwagandha, licorice, and marigold in a fungi-host specific manner

L Johny, DM Cahill, A Adholeya - Rhizosphere, 2021 - Elsevier
Strategies to enhance the production of secondary metabolites, derived from medicinal and
agriculturally important plants have been the subject of exploration to enable effective …

Exploring the industrial importance of a miracle herb Withania somnifera (L.) Dunal: Authentication through chemical profiling, in vitro studies and computational …

MI Tousif, M Nazir, M Saleem, S Tauseef, R Uddin… - Process …, 2022 - Elsevier
Withania somnifera (L.) Dunal has been identified as a miracle herb, thus the present study
was carried out to investigate W. somnifera growing in Cholistan Desert for its secondary …

Withaferin A protects against endoplasmic reticulum stress-associated apoptosis, inflammation, and fibrosis in the kidney of a mouse model of unilateral ureteral …

CM Chen, YP Chung, CH Liu, KT Huang, SS Guan… - Phytomedicine, 2020 - Elsevier
Background Withaferin A is a functional ingredient of a traditional medicinal plant, Withania
somnifera, which has been broadly used in India for protecting against chronic diseases …

Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV‐2 targeting main protease and papain‐like protease

S Choudhary, S Nehul, A Singh, PK Panda… - IUBMB …, 2024 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) may be over, but its variants continue to …

Investigation of CYP2B6, 3A4 and β-esterase interactions of Withania somnifera (L.) dunal in human liver microsomes and HepG2 cells

S Kumar, PJ Bouic, B Rosenkranz - Journal of ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Withania somnifera (L.) Dunal (Solanaceae) is a
traditional herb, used in African indigenous systems of medicine for the treatment of various …

Molecular docking and dynamics simulation reveal withanolides as potent antivirals against dengue virus

MF Lee, SL Tan, N Ahemad, AAA Hamid… - South African Journal of …, 2024 - Elsevier
The prevalence of dengue remains a significant global threat to public health with millions of
infections reported annually due to the lack of effective treatment options. Natural resources …