Interleukins in cancer: from biology to therapy
Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …
Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer
Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to
chemicals including polycyclic aromatic hydrocarbons (PAHs) and polychlorinated dibenzo …
chemicals including polycyclic aromatic hydrocarbons (PAHs) and polychlorinated dibenzo …
[HTML][HTML] T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
D Briukhovetska, J Suarez-Gosalvez, C Voigt… - Immunity, 2023 - cell.com
Although T cells can exert potent anti-tumor immunity, a subset of T helper (Th) cells
producing interleukin-22 (IL-22) in breast and lung tumors is linked to dismal patient …
producing interleukin-22 (IL-22) in breast and lung tumors is linked to dismal patient …
Dual Functions of T Lymphocytes in Breast Carcinoma: From Immune Protection to Orchestrating Tumor Progression and Metastasis
Simple Summary New insights into the foundation of cellular and molecular cancer
immunology have revealed that immune cells play crucial roles in the development and …
immunology have revealed that immune cells play crucial roles in the development and …
The role of Th22 cells, from tissue repair to cancer progression
H Doulabi, E Masoumi, M Rastin, AF Azarnaminy… - Cytokine, 2022 - Elsevier
Abstract CD4+ T helper (Th) cells play a significant role in modulating host defense. In the
presence of lineage specific cytokine cocktail, Naive CD4+ T cells can differentiate into …
presence of lineage specific cytokine cocktail, Naive CD4+ T cells can differentiate into …
Unveiling the mechanistic role of the Aryl hydrocarbon receptor in environmentally induced Breast cancer
P Chatterjee, S Banerjee - Biochemical Pharmacology, 2023 - Elsevier
The aryl hydrocarbon receptor (AhR) is a crucial cytosolic evolutionary conserved ligand-
activated transcription factor and a pleiotropic signal transducer. The biosensor activity of the …
activated transcription factor and a pleiotropic signal transducer. The biosensor activity of the …
Prevention and Co-management of breast cancer-related osteoporosis using resveratrol
Breast cancer (BC) is currently one of the most common cancers in women worldwide with a
rising tendency. Epigenetics, generally inherited variations in gene expression that occur …
rising tendency. Epigenetics, generally inherited variations in gene expression that occur …
The role of IL-22 in cancer
ZE Hunzeker, L Zhao, AM Kim, JM Parker, Z Zhu… - Medical Oncology, 2024 - Springer
Interleukin-22, discovered in the year of 2000, is a pleiotropic Th17 cytokine from the IL-10
family of cytokines. IL-22 signals through the type 2 cytokine receptor complex IL-22R and …
family of cytokines. IL-22 signals through the type 2 cytokine receptor complex IL-22R and …
A Critical Role of the IL-22–IL-22 Binding Protein Axis in Hepatocellular Carcinoma
AD Giannou, J Lücke, D Kleinschmidt, AM Shiri… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) still poses a major challenge for curative
treatment. Although some new therapeutic options arose during the last decade, the overall …
treatment. Although some new therapeutic options arose during the last decade, the overall …
IL-22 signaling in the tumor microenvironment
R Jiang, B Sun - Tumor microenvironment: the role of interleukins–part …, 2021 - Springer
Abstract Interleukin (IL)-22 belongs to the IL-10 cytokine family which performs biological
functions by binding to heterodimer receptors comprising a type 1 receptor chain (R1) and a …
functions by binding to heterodimer receptors comprising a type 1 receptor chain (R1) and a …