Electrical stimulation of the auricular vagus nerve (aVNS) is an emerging electroceutical
technology in the field of bioelectronic medicine with applications in therapy. Artificial …

Biophysical computational models are complementary to experiments and theories,
providing powerful tools for the study of neurological diseases. The focus of this review is the …

Current strategies for optimizing deep brain stimulation (DBS) therapy involve multiple
postoperative visits. During each visit, stimulation parameters are adjusted until desired …

High-frequency deep brain stimulation is used to treat a wide range of brain disorders, like
Parkinson's disease. The stimulated networks usually share common electrophysiological …

This study presents a computational model of closed-loop control of deep brain stimulation
(DBS) for Parkinson's disease (PD) to investigate clinically viable control schemes for …

Markers from local field potentials, neurochemicals, skin conductance, and hormone
concentrations have been proposed as a means of closing the loop in Deep Brain …

High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in
suppressing the motor symptoms of Parkinson's disease (PD). Current clinically-deployed …

Pharmacological neuromodulation strategies have shown limited efficacy in treating memory
deficits related to Alzheimer's disease (AD). Despite encouraging results from a few …

The hyperkinetic symptoms of Parkinson's Disease (PD) are associated with the ensembles
of interacting oscillators that cause excess or abnormal synchronous behavior within the …

Movement is planned and coordinated by the brain and carried out by contracting muscles
acting on specific joints. Motor commands initiated in the brain travel through descending …