Brain lipidomics: From functional landscape to clinical significance

JH Yoon, Y Seo, YS Jo, S Lee, E Cho… - Science …, 2022 - science.org
Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives

S Incontro, ML Musella, M Sammari… - Physiological …, 2025 - journals.physiology.org
Lipids represent the most abundant molecular type in the brain, with a fat content of∼ 60%
of the dry brain weight in humans. Despite this fact, little attention has been paid to …

[HTML][HTML] Amygdala activity and amygdala-hippocampus connectivity: metabolic diseases, dementia, and neuropsychiatric issues

J Song - Biomedicine & Pharmacotherapy, 2023 - Elsevier
With rapid aging of the population worldwide, the number of people with dementia is
dramatically increasing. Some studies have emphasized that metabolic syndrome, which …

Super-resolved trajectory-derived nanoclustering analysis using spatiotemporal indexing

TP Wallis, A Jiang, K Young, H Hou, K Kudo… - Nature …, 2023 - nature.com
Single-molecule localization microscopy techniques are emerging as vital tools to unravel
the nanoscale world of living cells by understanding the spatiotemporal organization of …

The DDHD2-STXBP1 interaction mediates long-term memory via generation of saturated free fatty acids

IO Akefe, SH Saber, B Matthews, BG Venkatesh… - The EMBO …, 2024 - embopress.org
The phospholipid and free fatty acid (FFA) composition of neuronal membranes plays a
crucial role in learning and memory, but the mechanisms through which neuronal activity …

Extraction, Isolation of Bioactive Compounds and Therapeutic Potential of Rapeseed (Brassica napus L.)

N Tileuberdi, A Turgumbayeva, B Yeskaliyeva… - Molecules, 2022 - mdpi.com
Rapeseed (Brassica napus L.) is a herbaceous annual plant of the Cruciferous family, the
Cabbage genus. This oilseed crop is widely used in many areas of industry and agriculture …

Overexpression of a MYB1 transcription factor enhances triacylglycerol and starch accumulation and biomass production in the green microalga Chlamydomonas …

J Zhao, Y Ge, K Liu, Y Yamaoka, D Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Microalgae are promising platforms for biofuel production. Transcription factors (TFs) are
emerging as key regulators of lipid metabolism for biofuel production in microalgae. We …

The phonon theory of liquids and biological fluids: Developments and applications

D Bolmatov - The Journal of Physical Chemistry Letters, 2022 - ACS Publications
Among the three basic states of matter (solid, liquid, and gas), the liquid state has always
eluded general theoretical approaches for describing liquid energy and heat capacity. In this …

Dual roles of coconut oil and its major component lauric acid on redox nexus: focus on cytoprotection and cancer cell death

V Ramya, KP Shyam, E Kowsalya… - Frontiers in …, 2022 - frontiersin.org
It has been reported that coconut oil supplementation can reduce neuroinflammation.
However, coconut oils are available as virgin coconut oil (VCO), crude coconut oil (ECO) …

Intestinal microbiota remodeling protects mice from western diet-induced brain inflammation and cognitive decline

PK Jena, T Setayesh, L Sheng, J Di Lucente, LW Jin… - Cells, 2022 - mdpi.com
It has been shown that the Western diet (WD) induces systemic inflammation and cognitive
decline. Moreover, probiotic supplementation and antibiotic treatment reduce diet-induced …