Controlling the excessive fracture burden in patients with chronic kidney disease (CKD)
Stages G4–G5D remains an impressive challenge. The reasons are 2-fold. First, the …

Patients with chronic kidney disease (CKD) exhibit tremendously elevated risk for
cardiovascular disease, particularly ischemic heart disease, due to premature vascular and …

Importance Dialysis-dependent patients experience high rates of morbidity from fractures,
yet little evidence is available on optimal treatment strategies. Chronic kidney disease …

Patients with CKD have a 4–fivefold higher rate of fractures. The incidence of fractures
increases with deterioration of kidney function. The process of skeletal changes in CKD …

Osteoporosis and fractures are common in persons with advanced chronic kidney disease
(CKD) and on maintenance dialysis. Although the diagnosis of osteoporosis in this …

Mineral and bone disorders including osteoporosis are common in dialysis patients and
contribute to increased morbimortality. However, whether denosumab and alendronate are …

Patients with chronic kidney disease (CKD) have an increased fracture risk because of
impaired bone quality and quantity. Low bone mineral density predicts fracture risk in all …

Hypocalcemia was reported at low rates (0.05–1.7%) in denosumab-treated
postmenopausal women with osteoporosis. This real-life study shows a 7.4% rate of …

People with chronic kidney disease (CKD) are at high risk of bone fractures. In this review,
we summarize the complexity of fracture prevention in CKD, describe the usefulness of a …

Evidence for the efficacy of denosumab in HD patients is limited. Accordingly, here we report
a study on the safety and efficacy of denosumab in these patients. We prospectively followed …