Chimeric antigen receptor (CAR) T cell therapy has emerged as one of the major
breakthroughs in cancer immunotherapy in the last decade. Outstanding results in …

Background Allogeneic hematopoietic stem cell transplantation (HSCT) can expose patients
to a transient but marked immunosuppression, during which viral infections are an important …

Cytomegalovirus (CMV) is one of the most common opportunistic infections that affect the
outcome of solid organ transplantation. This updated guideline from the American Society of …

T-cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have
been described in recovered patients, and may be important for immunity following infection …

Purpose: Viral infections are a major cause of morbidity and mortality following allogeneic
hematopoietic cell transplantation (allo-HCT). In the absence of safe and effective antiviral …

Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …

Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS,
transplant recipients, and fetuses, are at the highest risk for complications from …

Background Refractory CMV viremia and disease are associated with significant morbidity
and mortality in recipients of hematopoietic stem cell transplant (HCT). Methods In phase I/II …

While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …

Abstract Purpose of Review Cytomegalovirus (CMV) remains a major cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (Allo-HSCT). New …