Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …

A variety of fatty acids exists in the diet of humans, in the bloodstream of humans, and in
cells and tissues of humans. Fatty acids are energy sources and membrane constituents …

Objective To examine the traditional diet-heart hypothesis through recovery and analysis of
previously unpublished data from the Minnesota Coronary Experiment (MCE) and to put …

Macrophages are prominent immune cells in the tumor microenvironment that exert potent
effects on cancer metastasis. However, the signals and receivers for the tumor–macrophage …

Objective To evaluate the effectiveness of replacing dietary saturated fat with omega 6
linoleic acid, for the secondary prevention of coronary heart disease and death. Design …

Cellular membranes are composed of numerous kinds of glycerophospholipids with different
combinations of polar heads at the sn-3 position and acyl moieties at the sn-1 and sn-2 …

ABSTRACT A Western diet comprising high fat, high carbohydrate, and low fiber content has
been suggested to contribute to an increased prevalence of colitis. To clarify the effect of …

Being characterized by progressive and severe damage in neuronal cells,
neurodegenerative diseases (NDDs) are the major cause of disability and morbidity in the …

During the periparturient period, lipolysis in adipose tissue (AT) mobilizes fatty acid reserves
to meet high energy needs of dairy cows. This physiological response is accompanied by …

The composition of fatty acids in the diets of both human and domestic animal species can
regulate inflammation through the biosynthesis of potent lipid mediators. The substrates for …