TGF-β family signaling in early vertebrate development
TGF-β family ligands function in inducing and patterning many tissues of the early vertebrate
embryonic body plan. Nodal signaling is essential for the specification of mesendodermal …
embryonic body plan. Nodal signaling is essential for the specification of mesendodermal …
TGFβ family signaling and development
S Jia, A Meng - Development, 2021 - journals.biologists.com
The transforming growth factor β (TGFβ) signaling family is evolutionarily conserved in
metazoans. The signal transduction mechanisms of TGFβ family members have been …
metazoans. The signal transduction mechanisms of TGFβ family members have been …
Hemichordate genomes and deuterostome origins
Acorn worms, also known as enteropneust (literally,'gut-breathing') hemichordates, are
marine invertebrates that share features with echinoderms and chordates. Together, these …
marine invertebrates that share features with echinoderms and chordates. Together, these …
Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes
F Marlétaz, A Couloux, J Poulain, K Labadie… - Cell Genomics, 2023 - cell.com
Sea urchins are emblematic models in developmental biology and display several
characteristics that set them apart from other deuterostomes. To uncover the genomic cues …
characteristics that set them apart from other deuterostomes. To uncover the genomic cues …
Evolutionary crossroads in developmental biology: sea urchins
DR McClay - Development, 2011 - journals.biologists.com
Embryos of the echinoderms, especially those of sea urchins and sea stars, have been
studied as model organisms for over 100 years. The simplicity of their early development …
studied as model organisms for over 100 years. The simplicity of their early development …
RAS-independent ERK activation by constitutively active KSR3 in non-chordate metazoa
A Chessel, N De Crozé, MD Molina, L Taberner… - Nature …, 2023 - nature.com
During early development of the sea urchin embryo, activation of ERK signalling in
mesodermal precursors is not triggered by extracellular RTK ligands but by a cell …
mesodermal precursors is not triggered by extracellular RTK ligands but by a cell …
Homologous gene regulatory networks control development of apical organs and brains in Bilateria
R Feuda, IS Peter - Science Advances, 2022 - science.org
Apical organs are relatively simple larval nervous systems. The extent to which apical
organs are evolutionarily related to the more complex nervous systems of other animals …
organs are evolutionarily related to the more complex nervous systems of other animals …
Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network
Formation of the dorsal-ventral axis of the sea urchin embryo relies on cell interactions
initiated by the TGFβ Nodal. Intriguingly, although nodal expression is restricted to the …
initiated by the TGFβ Nodal. Intriguingly, although nodal expression is restricted to the …
Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm
A Saudemont, E Haillot, F Mekpoh, N Bessodes… - PLoS …, 2010 - journals.plos.org
Echinoderms, which are phylogenetically related to vertebrates and produce large numbers
of transparent embryos that can be experimentally manipulated, offer many advantages for …
of transparent embryos that can be experimentally manipulated, offer many advantages for …
Integration of canonical and noncanonical Wnt signaling pathways patterns the neuroectoderm along the anterior–posterior axis of sea urchin embryos
RC Range, RC Angerer, LM Angerer - PLoS biology, 2013 - journals.plos.org
Patterning the neuroectoderm along the anterior–posterior (AP) axis is a critical event in the
early development of deuterostome embryos. However, the mechanisms that regulate the …
early development of deuterostome embryos. However, the mechanisms that regulate the …