[HTML][HTML] Neurofilament light and glial fibrillary acidic protein in mood and anxiety disorders: A systematic review and meta-analysis

MJY Kang, J Grewal, D Eratne, C Malpas… - Brain, Behavior, and …, 2024 - Elsevier
Neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) are biomarkers of
neuronal injury measurable in cerebrospinal fluid (CSF) and blood. Despite their potential …

[HTML][HTML] Blood-Based Biomarkers in Frontotemporal Dementia: A Narrative Review

I Liampas, P Kyriakoulopoulou, V Karakoida… - International Journal of …, 2024 - mdpi.com
This narrative review explores the current landscape of blood biomarkers in Frontotemporal
dementia (FTD). Neurofilament light chain (NfL) may be useful in the differentiation of …

Elevated plasma neurofilament light and glial fibrillary acidic protein in epilepsy versus nonepileptic seizures and nonepileptic disorders

H Dobson, S Al Maawali, C Malpas, AF Santillo… - …, 2024 - Wiley Online Library
Objective Research suggests that recurrent seizures may lead to neuronal injury.
Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) levels …

[HTML][HTML] Plasma neurofilament light protein is differentially associated with age in individuals with treatment-resistant schizophrenia and bipolar affective disorder …

CMJ Wannan, D Eratne, AF Santillo, C Malpas… - Psychiatry …, 2024 - Elsevier
Accelerated brain ageing has been observed in multiple psychiatric disorders. This study
examined whether relationships between age and plasma neurofilament light (NfL) protein …

Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting

D Eratne, MJY Kang, C Lewis, C Dang… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION People with neurodegenerative disorders (ND) frequently face diagnostic
delay and misdiagnosis. We investigated blood and cerebrospinal fluid (CSF) neurofilament …

[HTML][HTML] Associations between structural brain changes and blood neurofilament light chain protein in treatment-resistant schizophrenia

BJ Cilia, D Eratne, C Wannan, C Malpas, S Janelidze… - medRxiv, 2024 - ncbi.nlm.nih.gov
Study Design Measurements of plasma NfL and cortical thickness were obtained from 39
individuals with TRS, and 43 healthy controls. T1-weighted magnetic resonance imaging …

[HTML][HTML] Plasma neurofilament light outperforms glial fibrillary acidic protein in differentiating behavioural variant frontotemporal dementia from primary psychiatric …

D Eratne, MJY Kang, C Lewis, C Dang… - Journal of the …, 2024 - Elsevier
Objective Timely, accurate distinction between behavioural variant frontotemporal dementia
(bvFTD) and primary psychiatric disorders (PPD) is a clinical challenge. Blood biomarkers …

[HTML][HTML] Neurofilament Light Protein as a Biomarker in Severe Mental Disorders: A Systematic Review

R Squitti, A Fiorenza, A Martinelli, V Brembati… - International Journal of …, 2024 - mdpi.com
Severe mental disorders (SMDs), such as schizophrenia (SZ), bipolar disorder (BD), and
major depressive disorder (MDD), are heterogeneous psychiatric diseases that impose a …

Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical cohort

D Eratne, QX Li, C Lewis, C Dang, MJY Kang… - Journal of …, 2025 - Springer
Objective We investigated diagnostic utility of phosphorylated tau 217 and 181 (ptau217,
ptau181), glial fibrillary acidic protein (GFAP), amyloid beta 42 and 40 (Aβ42, Aβ40), and …

Using cerebrospinal fluid biomarkers to diagnose Alzheimer's disease: an Australian perspective

D Eratne, S Collins, PJ Nestor, D Pond… - Frontiers in …, 2024 - frontiersin.org
Cerebrospinal fluid (CSF) biomarkers are currently the only clinically validated biofluid
diagnostic test for Alzheimer's Disease (AD) available in Australia. Testing of CSF …