Cancer-cell-targeted theranostic cubosomes

C Caltagirone, AM Falchi, S Lampis, V Lippolis, V Meli… - Langmuir, 2014 - ACS Publications
This work was devoted to the development of a new type of lipid-based (cubosome)
theranostic nanoparticle able to simultaneously host camptothecin, a potent anticancer drug …

Solubilization and stabilization of camptothecin in micellar solutions of pluronic-g-poly (acrylic acid) copolymers

R Barreiro-Iglesias, L Bromberg, M Temchenko… - Journal of controlled …, 2004 - Elsevier
The capability of a family of copolymers comprising Pluronic®(PEO-PPO-PEO) surfactants
covalently conjugated with poly (acrylic acid)(Pluronic-PAA) to enhance the aqueous …

Terminating the criminal collaboration in pancreatic cancer: nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance

L Wang, X Liu, Q Zhou, M Sui, Z Lu, Z Zhou, J Tang… - Biomaterials, 2017 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a dismal overall prognosis
mainly unchanged over the past decades. PDAC is generally refractory to conventional …

Ophiorrhiza, a promising herbaceous source of the anticancer compound camptothecin

G Krishnakumar, KP Dintu, SC Varghese… - Plant Science …, 2020 - horizonepublishing.com
Camptothecin is an important source for the synthesis of some of the major anti-cancer
agents such as irinotecan and topotecan. Traditional source of camptothecin are …

Fluorescence studies of anti-cancer drugs-analytical and biomedical applications

JJ Aaron, S Trajkovska - Current Drug Targets, 2006 - ingentaconnect.com
The fluorescence properties of anticancer drugs (ACDs), including steady-state native
fluorescence, time-resolved fluorescence, fluorescence polarization, excimer and exciplex …

Synthesis and properties of a functional copolymer from N-ethylaniline and aniline by an emulsion polymerization

XG Li, HJ Zhou, MR Huang - Polymer, 2005 - Elsevier
A series of functional copolymers was synthesized by an emulsion polymerization of N-
ethylaniline (EA) and aniline (AN) in the presence of sodium dodecylbenzene sulfonate in …

Experimental and theoretical investigation of the molecular and electronic structure of anticancer drug camptothecin

N Subramanian, N Sundaraganesan, S Sudha… - … Acta Part A: Molecular …, 2011 - Elsevier
The Fourier Transform Infrared spectrum of (S)-4 ethyl-4-hydroxy-1H-pyrano [3′, 4′: 6, 7]-
indolizino-[1, 2-b-quinoline-3, 14-(4H, 12H)-dione][camptothecin] was recorded in the region …

Theoretical analysis of lactone and carboxylate forms of camptothecin in aqueous solution: Electronic states, absorption spectra, and hydration

VV Kostjukov - Journal of Molecular Liquids, 2021 - Elsevier
The vibronic absorption spectra of the camptothecin drug in an aqueous solution have been
calculated for the first time. The calculations were carried out by the TD-DFT method. It was …

Excited-State Proton Transfer Reactions of 10-Hydroxycamptothecin1

KM Solntsev, EN Sullivan, LM Tolbert… - Journal of the …, 2004 - ACS Publications
Time-resolved and steady-state emission characterization of 10-hydroxycamptothecin
reveals a rich but less complex proton-transfer behavior than its parent hydroxyquinoline …

UV− Vis Spectra of the Anticancer Campothecin Family Drugs in Aqueous Solution: Specific Spectroscopic Signatures Unraveled by a Combined Computational and …

N Sanna, G Chillemi, L Gontrani, A Grandi… - The Journal of …, 2009 - ACS Publications
The ultraviolet− visible absorption spectrum of camptothecin (CPT) has been been recorded
in aqueous solution at pH 5.3, where the equilibrium among the different CPT forms is …