Bacteria–surface interactions

HH Tuson, DB Weibel - Soft matter, 2013 - pubs.rsc.org
The interaction of bacteria with surfaces has important implications in a range of areas,
including bioenergy, biofouling, biofilm formation, and the infection of plants and animals …

Reducing bacterial infections and biofilm formation using nanoparticles and nanostructured antibacterial surfaces

G Mi, D Shi, M Wang, TJ Webster - Advanced Healthcare …, 2018 - Wiley Online Library
With the rapid spreading of resistance among common bacterial pathogens, bacterial
infections, especially antibiotic‐resistant bacterial infections, have drawn much attention …

Catch-bond mechanism of the bacterial adhesin FimH

MM Sauer, RP Jakob, J Eras, S Baday, D Eriş… - Nature …, 2016 - nature.com
Ligand–receptor interactions that are reinforced by mechanical stress, so-called catch-
bonds, play a major role in cell–cell adhesion. They critically contribute to widespread …

Targeting the bacteria–host interface: strategies in anti-adhesion therapy

AM Krachler, K Orth - Virulence, 2013 - Taylor & Francis
Bacterial infections are a major cause of morbidity and mortality worldwide and are
increasingly problematic to treat due to the rise in antibiotic-resistant strains. It becomes …

Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH–oligomannose-3 complex

A Wellens, C Garofalo, H Nguyen, N Van Gerven… - PLoS one, 2008 - journals.plos.org
Background Escherichia coli strains adhere to the normally sterile human uroepithelium
using type 1 pili, that are long, hairy surface organelles exposing a mannose-binding FimH …

Structural basis for mechanical force regulation of the adhesin FimH via finger trap-like β sheet twisting

I Le Trong, P Aprikian, BA Kidd, M Forero-Shelton… - Cell, 2010 - cell.com
The Escherichia coli fimbrial adhesive protein, FimH, mediates shear-dependent binding to
mannosylated surfaces via force-enhanced allosteric catch bonds, but the underlying …

Catch bonds in adhesion

W Thomas - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
One of the most exciting discoveries in biological adhesion is the recent and counter-
intuitive observation that the lifetimes of some biological adhesive bonds, called catch …

FimH forms catch bonds that are enhanced by mechanical force due to allosteric regulation

O Yakovenko, S Sharma, M Forero… - Journal of Biological …, 2008 - ASBMB
The bacterial adhesive protein, FimH, is the most common adhesin of Escherichia coli and
mediates weak adhesion at low flow but strong adhesion at high flow. There is evidence that …

[HTML][HTML] Catch-bond mechanism of force-enhanced adhesion: counterintuitive, elusive, but… widespread?

EV Sokurenko, V Vogel, WE Thomas - Cell host & microbe, 2008 - cell.com
Catch bonds are bonds between a ligand and its receptor that are enhanced by mechanical
force pulling the ligand-receptor complex apart. To date, catch-bond formation has been …

Environmental influences on biofilm development

CC Goller, T Romeo - Bacterial Biofilms, 2008 - Springer
Bacterial biofilms are found under diverse environmental conditions, from sheltered and
specialized environments found within mammalian hosts to the extremes of biological …