With the rapid spreading of resistance among common bacterial pathogens, bacterial infections, especially antibiotic‐resistant bacterial infections, have drawn much attention …
Ligand–receptor interactions that are reinforced by mechanical stress, so-called catch- bonds, play a major role in cell–cell adhesion. They critically contribute to widespread …
Bacterial infections are a major cause of morbidity and mortality worldwide and are increasingly problematic to treat due to the rise in antibiotic-resistant strains. It becomes …
A Wellens, C Garofalo, H Nguyen, N Van Gerven… - PLoS one, 2008 - journals.plos.org
Background Escherichia coli strains adhere to the normally sterile human uroepithelium using type 1 pili, that are long, hairy surface organelles exposing a mannose-binding FimH …
The Escherichia coli fimbrial adhesive protein, FimH, mediates shear-dependent binding to mannosylated surfaces via force-enhanced allosteric catch bonds, but the underlying …
W Thomas - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
One of the most exciting discoveries in biological adhesion is the recent and counter- intuitive observation that the lifetimes of some biological adhesive bonds, called catch …
O Yakovenko, S Sharma, M Forero… - Journal of Biological …, 2008 - ASBMB
The bacterial adhesive protein, FimH, is the most common adhesin of Escherichia coli and mediates weak adhesion at low flow but strong adhesion at high flow. There is evidence that …
EV Sokurenko, V Vogel, WE Thomas - Cell host & microbe, 2008 - cell.com
Catch bonds are bonds between a ligand and its receptor that are enhanced by mechanical force pulling the ligand-receptor complex apart. To date, catch-bond formation has been …
Bacterial biofilms are found under diverse environmental conditions, from sheltered and specialized environments found within mammalian hosts to the extremes of biological …