Clinical research is an alternative terminology used to describe medical research. Clinical
research involves people, and it is generally carried out to evaluate the efficacy of a …

Abstract Purpose of Review Innovative clinical trial designs for glioblastoma (GBM) are
needed to expedite drug discovery. Phase 0, window of opportunity, and adaptive designs …

While interest in the application of machine learning to improve healthcare has grown
tremendously in recent years, a number of barriers prevent deployment in medical practice …

Abstract The National Heart, Lung, and Blood Institute convened a workshop in August 2021
to identify opportunities in pediatric and congenital cardiovascular research that would …

Background Trial design plays a key role in clinical trials. Traditional group sequential
design has been used in cardiovascular clinical trials over decades as the trials can …

Healthcare data analysis has emerged as one of the most promising fields of study in recent
years. There are different types of data in the healthcare industry, such as medical test …

Recent significant advances in the healthcare industry due to artificial intelligence (AI) and
machine learning (ML) have been shown to revolutionize healthcare delivery by improving …

Background Globally, there is a growing focus on efficient trials, yet numerous
interpretations have emerged, suggesting a significant heterogeneity in understanding …

Adaptive designs are increasingly developed and used to improve all phases of clinical
trials and in biomedical studies in various ways to address different statistical issues. We first …

Background/Objectives: The dual forces of structured inquiry and serendipitous discovery
have long shaped neuropsychiatric research, with groundbreaking treatments such as …