Rare actinomycetes are a source of numerous diverse, biologically active secondary
metabolites, including macrolides, which have been shown to display several antibiotic …

Biofouling is the assemblage of undesirable biological materials and macro-organisms
(barnacles, mussels, etc.) on submerged surfaces, which has unfavorable impacts on the …

Metabolomics experiments generate highly complex datasets, which are time and work-
intensive, sometimes even error-prone if inspected manually. Therefore, new methods for …

Kutzneria is a rare genus of Actinobacteria that harbors a variety of secondary metabolite
gene clusters and produces several interesting types of bioactive secondary metabolites …

Two new chloropyrroles, designated catellatopyrroles A (1) and B (2), along with 2-(2′-
hydroxybenzoyl) pyrrole (3), were isolated from a culture extract of an actinomycete of the …

Actinobacteria are one of the most intriguing bacterial phyla in terms of chemical diversity
and bioactivities of their reported biomolecules and natural products, including various types …

Isoquinolinequinones represent an important family of natural alkaloids with profound
biological activities. Heterologous expression of a rare bifunctional indole prenyltransferase …

Gargantulides B and C, two new and highly complex 52-membered glycosylated
macrolactones, were isolated from Amycolatopsis sp. strain CA-230715 during an …

Polyketides are a major class of natural products, including bioactive medicines such as
erythromycin and rapamycin. They are often rich in stereocenters biosynthesized by the …

Actinobacteria are well known as a rich source of diversity of bioactive secondary
metabolites. Kutzneria, a rare actinobacteria belonging to the family Pseudonocardiaceae …