OV Modulators of the Paediatric Brain TIME: Current Status, Combination Strategies, Limitations and Future Directions

K Vazaios, RE van Berkum, FG Calkoen… - International Journal of …, 2024 - mdpi.com
Oncolytic viruses (OVs) are characterised by their preference for infecting and replicating in
tumour cells either naturally or after genetic modification, resulting in oncolysis. Furthermore …

Gene expression signatures predict the sensitivity of pediatric brain tumors to different oncolytic viruses

FT Demir, H Wakimoto - Molecular Therapy Oncology, 2024 - cell.com
As the most frequent solid tumor in children, pediatric central nervous system (CNS)
malignancies are the leading cause of cancerrelated mortality in the age range of 0–18. 1 To …