Abstract Peptide Nucleic Acids (PNAs) are the DNA/RNA analogues in which sugar-
phosphate backbone is replaced by N-2-aminoethylglycine repeating units. PNA contains …

The analogs of DNA are unique biomedical tools that are broadly utilized to develop
different types of biosensors. Peptide nucleic acids (PNA) are an individual and notable …

Antibiotic resistance is an escalating, worldwide problem. Due to excessive use of
antibiotics, multidrug-resistant bacteria have become a serious threat and a major global …

Conjugation of chitosan with nucleobases is expected to expand its not only antimicrobial
activity but also anti-cancer activity. Here, we report the synthesis of a novel chitosan …

Abstract Peptide Nucleic Acid (PNA) are DNA/RNA synthetic analogs with 2‐([2‐aminoethyl]
amino) acetic acid backbone. They partake unique antisense and antigene properties, just …

Nature encodes the information required for life in two fundamental biopolymers: nucleic
acids and proteins. Peptide nucleic acid (PNA), a synthetic analog comprised of …

A new biopolymer dye containing naphthalimide moiety was synthesized by reaction of N-
naphthaloyl chitosan with 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-piperazino-3 …

PNAs are emerging as useful synthetic devices targeting natural miRNAs. In particular 3
classes of structurally modified PNAs analogs are herein described, namely α, β and γ …

Here we report the solid phase synthesis and characterization (LC-ESIMS, CD) of a cationic
nucleobase-containing α-peptide, composed of both L-arginine residues and L-lysine-based …

Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral
pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding …