The cancer spliceome: reprograming of alternative splicing in cancer
E El Marabti, I Younis - Frontiers in molecular biosciences, 2018 - frontiersin.org
Alternative splicing allows for the expression of multiple RNA and protein isoforms from one
gene, making it a major contributor to transcriptome and proteome diversification in …
gene, making it a major contributor to transcriptome and proteome diversification in …
NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age
GK Gray, BC McFarland, SE Nozell… - Expert review of …, 2014 - Taylor & Francis
Since we last addressed the roles of NF-κB and JAK/STAT3 signaling in glioblastoma (GBM)
5 years ago, tremendous strides have been made in the understanding of these two …
5 years ago, tremendous strides have been made in the understanding of these two …
Development of T cells redirected to glypican-3 for the treatment of hepatocellular carcinoma
H Gao, K Li, H Tu, X Pan, H Jiang, B Shi, J Kong… - Clinical Cancer …, 2014 - AACR
Purpose: The aim of our study is to elucidate whether T cells expressing GPC3-targeted
chimeric antigen receptor (CAR) can efficiently eliminate GPC3-positive HCC cells and their …
chimeric antigen receptor (CAR) can efficiently eliminate GPC3-positive HCC cells and their …
Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors
Although the development of multiple primary tumors in smokers with lung cancer can be
attributed to carcinogen-induced field cancerization, the occurrence of multiple tumors at …
attributed to carcinogen-induced field cancerization, the occurrence of multiple tumors at …
MicroRNA-210-3p is transcriptionally upregulated by hypoxia induction and thus promoting EMT and chemoresistance in glioma cells
H Liu, C Chen, J Zeng, Z Zhao, Q Hu - PLoS One, 2021 - journals.plos.org
Background Glioma is the most common and lethal form of brain cancer. It is highly
malignant and is often characterized by chemoresistance and radioresistance, which are …
malignant and is often characterized by chemoresistance and radioresistance, which are …
M1 to M2 macrophage polarization in heparin-binding epidermal growth factor-like growth factor therapy for necrotizing enterocolitis
J Wei, GE Besner - Journal of Surgical Research, 2015 - Elsevier
Background Macrophages can be polarized into proinflammatory (M1) and anti-
inflammatory (M2) subtypes. However, whether macrophage polarization plays a role in …
inflammatory (M2) subtypes. However, whether macrophage polarization plays a role in …
Development of self-assembling peptide nanovesicle with bilayers for enhanced EGFR-targeted drug and gene delivery
X Liang, B Shi, K Wang, M Fan, D Jiao, J Ao, N Song… - Biomaterials, 2016 - Elsevier
Abstract Development of rational vectors for efficient drug and gene delivery is crucial for
cancer treatment. In this study, epidermal growth factor receptor (EGFR)-binding peptide …
cancer treatment. In this study, epidermal growth factor receptor (EGFR)-binding peptide …
Selective targeting of glioblastoma with EGFRvIII/EGFR bitargeted chimeric antigen receptor T cell
H Jiang, H Gao, J Kong, B Song, P Wang, B Shi… - Cancer immunology …, 2018 - AACR
The heterogeneous expression of EGFRvIII [variant III mutant of epidermal growth factor
receptor (EGFR)] in glioblastoma has significant impact on the clinical response to the …
receptor (EGFR)] in glioblastoma has significant impact on the clinical response to the …
miR-542-5p attenuates fibroblast activation by targeting integrin α6 in silica-induced pulmonary fibrosis
J Yuan, P Li, H Pan, Y Li, Q Xu, T Xu, X Ji, Y Liu… - International Journal of …, 2018 - mdpi.com
Silicosis is a very serious occupational disease and it features pathological manifestations of
inflammatory infiltration, excessive proliferation of fibroblasts and massive depositions of the …
inflammatory infiltration, excessive proliferation of fibroblasts and massive depositions of the …
Hypoxia activates enhanced invasive potential and endogenous hyaluronic acid production by glioblastoma cells
Glioblastoma (GBM) is the most common, aggressive, and deadly form of adult brain cancer,
and is associated with a short survival rate (median 12–15 months, 5+ year less than 5%) …
and is associated with a short survival rate (median 12–15 months, 5+ year less than 5%) …