Engineered living materials for sustainability

B An, Y Wang, Y Huang, X Wang, Y Liu, D Xun… - Chemical …, 2022 - ACS Publications
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Proliferating active matter

O Hallatschek, SS Datta, K Drescher, J Dunkel… - Nature Reviews …, 2023 - nature.com
The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

Programming multicellular assembly with synthetic cell adhesion molecules

AJ Stevens, AR Harris, J Gerdts, KH Kim, C Trentesaux… - Nature, 2023 - nature.com
Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell–
cell interactions in processes as diverse as tissue development, immune cell trafficking and …

Targeted bacterial conjugation mediated by synthetic cell-to-cell adhesions

M Robledo, B Álvarez, A Cuevas… - Nucleic Acids …, 2022 - academic.oup.com
Genetic interventions on microbiomes, for clinical or biotechnological purposes, remain
challenging. Conjugation-based delivery of genetic cargo is still unspecific and limited by …

Dynamic Growth of Macroscopically Structured Supramolecular Hydrogels through Orchestrated Reaction‐Diffusion

H Wang, X Fu, G Gu, S Bai, R Li… - Angewandte Chemie …, 2023 - Wiley Online Library
Living organisms are capable of dynamically changing their structures for adaptive functions
through sophisticated reaction‐diffusion processes. Here we show how active …

[HTML][HTML] A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

DS Glass, A Bren, E Vaisbourd, A Mayo, U Alon - Cell, 2024 - cell.com
Differentiation is crucial for multicellularity. However, it is inherently susceptible to mutant
cells that fail to differentiate. These mutants outcompete normal cells by excessive self …

Engineering heterogeneous tumor models for biomedical applications

Z Wu, D Huang, J Wang, Y Zhao, W Sun… - Advanced …, 2024 - Wiley Online Library
Tumor tissue engineering holds great promise for replicating the physiological and
behavioral characteristics of tumors in vitro. Advances in this field have led to new …

Cell-selective multifunctional surface covalent reconfiguration using aptamer-enabled proximity catalytic labeling

Y Guo, N Wang, Y Zhong, W Li, Y Li… - Journal of the …, 2023 - ACS Publications
Cell surface engineering provides access to custom-made cell interfaces with desirable
properties and functions. However, cell-selective covalent labeling methods that can …

A whole-cell platform for discovering synthetic cell adhesion molecules in bacteria

PY Chen, YC Chen, PP Chen, KT Lin… - Nature …, 2024 - nature.com
Developing programmable bacterial cell-cell adhesion is of significant interest due to its
versatile applications. Current methods that rely on presenting cell adhesion molecules …

Identifying LasR Quorum Sensors with Improved Signal Specificity by Mapping the Sequence–Function Landscape

M Zeng, B Sarker, SN Rondthaler, V Vu… - ACS Synthetic …, 2024 - ACS Publications
Programmable intercellular signaling using components of naturally occurring quorum
sensing can allow for coordinated functions to be engineered in microbial consortia. LuxR …