Hepatocellular carcinoma is the most prevalent form of primary liver cancer with a
multifactorial aetiology comprising genetic, environmental, and behavioural factors. Evading …

Cancer is a multifactorial, multi-stage disease, including complex cascades of signaling
pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the …

Hepatocellular carcinoma (HCC) is a leading cause of death, resulting in over 700 thousand
deaths annually worldwide. Chemotherapy is the primary therapeutic strategy for patients …

Despite the huge investment into research and the significant effort and advances made in
the search for new anticancer drugs in recent decades, cancer cure and treatment continue …

In the last decades researchers of natural products chemistry focused their research in a
wide variety of bioactive compounds from marine species. Marine sponges (Porifera) have …

Natural compounds derived from marine organisms exhibit a wide variety of biological
activities. Over the last decades, a great interest has been focused on the anti-tumour role of …

Cancer is considered as one of the deadliest diseases in the medical field. Apart from the
preventive therapies, it is important to find a curative measure which holds no loopholes and …

Inhibition of apoptosis leads to activation of cell survival factors (eg, AKT) causes continuous
cell proliferation in cancer. Apoptosis, the major form of cellular suicide, is central to various …

This study aims to identify bioactive anticancer and anti-trypanosome secondary metabolites
from the fermentation culture of Aspergillus flocculus endophyte assisted by modern …

Several reviews of inhibitors of topoisomerase II have been published, covering research
before 2018. Therefore, this review is focused primarily on more recent publications with …