Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and …
EK Elmahallawy, AS Martínez… - The Journal of Infection …, 2014 - jidc.org
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses …
WW Zhang, S Karmakar, S Gannavaram, R Dey… - Nature …, 2020 - nature.com
Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa transmitted by infected sand flies. Vaccination through leishmanization with live Leishmania major has …
Protozoan parasites of the Leishmania donovani complex–L. donovani and L. infantum– cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome …
R El-Awady, E Saleh, A Hashim, N Soliman… - Frontiers in …, 2017 - frontiersin.org
Over the years chemotherapy failure has been a vital research topic as researchers have been striving to discover reasons behind it. The extensive studies carried out on …
Carbohydrate antigens have shown promise as important targets for developing effective vaccines and pathogen detection strategies. Modifying purified microbial glycans through …
M Moriconi, G Rugna, M Calzolari… - PLoS neglected …, 2017 - journals.plos.org
Pathogens transmitted to humans by phlebotomine sand flies are neglected, as they cause infectious diseases that are not on the priority list of national and international public health …
AA Bekhit, E El-Agroudy, A Helmy, TM Ibrahim… - European journal of …, 2018 - Elsevier
Leishmaniasis affects over 150 million people all over the world, especially in subtropical regions. Currently used antileishmanial synthesized drugs are associated with some …
P Yadav, M Azam, V Ramesh, R Singh - Pathogens, 2023 - mdpi.com
Leishmaniasis significantly affects the population of the tropics and subtropics. Clinical features and infective species of Leishmania are the primary factors driving the direction of …