Recent advances in the synthesis of bioactive glycohybrids via click-chemistry

K Singh, R Tyagi, VK Mishra, G Tiwari, R Sagar - SynOpen, 2023 - thieme-connect.com
Carbohydrates, traditionally known for their energy-providing role, have gained significant
attention in drug discovery due to their diverse bioactivities and stereodiversity. However …

Pd(II)-Catalyzed Cascade Annulation of o-Aminobenzoic Acids with CO, Amines, and Aldehydes to N3-/N1,N3-Substituted 2,3-Dihydroquinazolin-4(1H)-ones

X Zhang, J Wang, J Xu, Q Pang, D Liu… - The Journal of Organic …, 2023 - ACS Publications
The unprecedented Pd (II)-catalyzed cascade annulation of o-aminobenzoic acids with CO,
amines, and aldehydes has been developed. This protocol provides an efficient and concise …

Synthesis and antiplasmodial activity of glyco-conjugate hybrids of phenylhydrazono-indolinones and glycosylated 1, 2, 3-triazolyl-methyl-indoline-2, 3-diones

RK Thakur, P Joshi, P Baranwal, G Sharma… - European Journal of …, 2018 - Elsevier
A small library of 36 new glycohybrids of phenylhydrazono-indolinones was synthesized
employing glycosylated 1, 2, 3-triazolyl-methyl-indoline-2, 3-diones and different …

Synthesis and antimicrobial activity of novel 1, 2, 3‐triazole‐conjugates of quinazolin‐4‐ones

IE Głowacka, P Grzonkowski, P Lisiecki… - Archiv der …, 2019 - Wiley Online Library
A novel series of diethyl {4‐[(4‐oxoquinazolin‐3 (4H)‐yl) methyl]‐1H‐1, 2, 3‐triazol‐1‐yl}
alkylphosphonates 9aa–aj and their respective derivatives substituted at C6 of the …

Modular strategy to expand the chemical diversity of DNA and sequence-controlled polymers

D de Rochambeau, Y Sun, M Barlog… - The Journal of …, 2018 - ACS Publications
Sequence-defined polymers with customizable sequences, monodispersity, substantial
length, and large chemical diversity are of great interest to mimic the efficiency and …

Synthetic approach to novel glycosyltriazole-3-hydroxyquinolone conjugates and their antimicrobial properties

V Šamšulová, M Poláková, R Horák, M Šedivá… - Journal of Molecular …, 2019 - Elsevier
A synthetic approach to novel 2-(1-glycosyl-1, 2, 3-triazol-4-yl)-3-hydroxyquinolone
conjugates has been developed. The methodology involves preparation of a suitable …

d-Idose-Based Monoaza-15-Crown-5 Lariat Ethers: Synthesis of an Elusive d-Hexose and Application of Derived Macrocycles in Enantioselective Syntheses

I Orbán, D Ujj, B Mátravölgyi, T Holczbauer, Z Rapi - Symmetry, 2023 - mdpi.com
Carbohydrate-based macrocycles can be enantioselective catalysts in certain reactions.
Previously, it was proven that the carbohydrate moiety could affect the catalytic activity of the …

Syntheses of two kinds of disaccharide subunits of antitumor antibiotic bleomycins

R Che, Q Zhu, J Yu, J Li, J Yu, W Lu - Tetrahedron, 2017 - Elsevier
Gram-scale syntheses of two kinds of bleomycin disaccharides are described. l-gulose
subunit 12 was accomplished with a novel and short route in six steps and 37% overall yield …

Syntheses and domino ring closure reactions of novel N-propargyl-substituted alicyclic β-amino acids

M El Haimer - 2022 - search.proquest.com
Simple and efficient routes have been developed for the preparation of new racemic and
enantiomeric cis-and trans-cyclohexene-, cyclohexane-, diendo-and diexo-norbornene-and …

Five-membered ring systems: With more than one N atom

L Yet - Progress in Heterocyclic Chemistry, 2018 - Elsevier
Five-Membered Ring Systems: With More Than One N Atom - ScienceDirect Skip to main
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