Noncancerous disease-targeting AIEgens

Y Duo, G Luo, W Zhang, R Wang, GG Xiao… - Chemical Society …, 2023 - pubs.rsc.org
Noncancerous diseases include a wide plethora of medical conditions beyond cancer and
are a major cause of mortality around the world. Despite progresses in clinical research …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

Aggregation‐induced emission‐active gels: fabrications, functions, and applications

Z Li, X Ji, H Xie, BZ Tang - Advanced Materials, 2021 - Wiley Online Library
Chromophores that exhibit aggregation‐induced emission (ie, aggregation‐induced
emission luminogens [AIEgens]) emit intense fluorescence in their aggregated states, but …

1, 8-Naphthalimide-based fluorescent chemosensors: recent advances and perspectives

HQ Dong, TB Wei, XQ Ma, QY Yang… - Journal of Materials …, 2020 - pubs.rsc.org
1, 8-Naphthalimide, as one of the classical dyes and fluorophores, has been widely used in
analytical chemistry, materials chemistry, and biochemistry fields because of its excellent …

Construction of Long‐Wavelength Emissive Organic Nanosonosensitizer Targeting Mitochondria for Precise and Efficient In Vivo Sonotherapy

X Zhang, C Li, Y Zhang, X Guan, L Mei… - Advanced Functional …, 2022 - Wiley Online Library
As a modern biomedical therapeutic modality, sonodynamic therapy (SDT) presents unique
advantages, including superior tissue penetration capability, temporal–spatial controllability …

Pillar [5] arene‐Modified Gold Nanorods as Nanocarriers for Multi‐Modal Imaging‐Guided Synergistic Photodynamic‐Photothermal Therapy

N Song, Z Zhang, P Liu, D Dai, C Chen… - Advanced Functional …, 2021 - Wiley Online Library
Supramolecular approaches have opened up vast possibilities to construct versatile
materials, especially those with stimuli‐responsiveness and integrated functionalities of …

[HTML][HTML] Biomedical application of aggregation-induced emission luminogen-based fluorescent sensors

Y Duo, Z Xiang, G Gao, G Luo, BZ Tang - TrAC Trends in Analytical …, 2023 - Elsevier
Fluorescent biosensors are powerful analytical tools that have been widely employed in a
range of in vitro and in vivo biomedical applications. However, traditional fluorophores …

Molecular engineering to accelerate cancer cell discrimination and boost AIE-active type I photosensitizer for photodynamic therapy under hypoxia

X Zhao, Y Dai, F Ma, S Misal, K Hasrat, H Zhu… - Chemical Engineering …, 2021 - Elsevier
The severe hypoxia in solid tumor and the accurate discrimination between cancer and
normal cells gravely restrict the application of fluorescence imaging-guided photodynamic …

Single fluorescent probes enabling simultaneous visualization of duple organelles: Design principles, mechanisms, and applications

M Tian, J Zhan, W Lin - Coordination Chemistry Reviews, 2022 - Elsevier
A unique kind of fluorescent probes which can target duple organelles have been
continuously presented in very recent years. These probes have demonstrated great …

[HTML][HTML] Combination of bacterial-targeted delivery of gold-based AIEgen radiosensitizer for fluorescence-image-guided enhanced radio-immunotherapy against …

Y Duo, Z Chen, Z Li, X Li, Y Yao, T Xu, G Gao, G Luo - Bioactive Materials, 2023 - Elsevier
Abstract Aggregation-Induced Emission luminogen (AIEgen) possess great potential in
enhancing bioimaging-guided radiotherapeutic effects and radioimmunotherapy to improve …