Structures and general transport mechanisms by the major facilitator superfamily (MFS)

D Drew, RA North, K Nagarathinam… - Chemical reviews, 2021 - ACS Publications
The major facilitator superfamily (MFS) is the largest known superfamily of secondary active
transporters. MFS transporters are responsible for transporting a broad spectrum of …

The effects of temperature on aerobic metabolism: towards a mechanistic understanding of the responses of ectotherms to a changing environment

PM Schulte - The Journal of experimental biology, 2015 - journals.biologists.com
Because of its profound effects on the rates of biological processes such as aerobic
metabolism, environmental temperature plays an important role in shaping the distribution …

How close are we to the temperature tipping point of the terrestrial biosphere?

KA Duffy, CR Schwalm, VL Arcus, GW Koch… - Science …, 2021 - science.org
The temperature dependence of global photosynthesis and respiration determine land
carbon sink strength. While the land sink currently mitigates~ 30% of anthropogenic carbon …

Temperature responses of ecosystem respiration

S Niu, W Chen, LL Liáng, CA Sierra, J Xia… - Nature Reviews Earth & …, 2024 - nature.com
Abstract Terrestrial ecosystems release~ 106–130 PgC yr–1 into the atmosphere through
respiration, counterbalancing photosynthetic carbon uptake and determining the strength of …

Computational design of the temperature optimum of an enzyme reaction

F van der Ent, S Skagseth, BA Lund, J Sočan… - Science …, 2023 - science.org
Cold-adapted enzymes are characterized both by a higher catalytic activity at low
temperatures and by having their temperature optimum down-shifted, compared to …

On the temperature dependence of enzyme-catalyzed rates

VL Arcus, EJ Prentice, JK Hobbs, AJ Mulholland… - Biochemistry, 2016 - ACS Publications
One of the critical variables that determine the rate of any reaction is temperature. For
biological systems, the effects of temperature are convoluted with myriad (and often …

New Insights into the Cooperativity and Dynamics of Dimeric Enzymes

KW Chen, TY Sun, YD Wu - Chemical Reviews, 2023 - ACS Publications
A survey of protein databases indicates that the majority of enzymes exist in oligomeric
forms, with about half of those found in the UniProt database being homodimeric …

Evolutionary drivers of thermoadaptation in enzyme catalysis

V Nguyen, C Wilson, M Hoemberger, JB Stiller… - Science, 2017 - science.org
With early life likely to have existed in a hot environment, enzymes had to cope with an
inherent drop in catalytic speed caused by lowered temperature. Here we characterize the …

Thermodynamic theory explains the temperature optima of soil microbial processes and high Q10 values at low temperatures

LA Schipper, JK Hobbs, S Rutledge… - Global change …, 2014 - Wiley Online Library
Our current understanding of the temperature response of biological processes in soil is
based on the Arrhenius equation. This predicts an exponential increase in rate as …

Evaluating the Arrhenius equation for developmental processes

J Crapse, N Pappireddi, M Gupta… - Molecular systems …, 2021 - embopress.org
The famous Arrhenius equation is well suited to describing the temperature dependence of
chemical reactions but has also been used for complicated biological processes. Here, we …