There is an immediate need to drastically reduce the emissions associated with global fossil
fuel consumption in order to limit climate change. However, carbon-based materials …

Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

Clostridium difficile is an emergent pathogen, and the most common cause of nosocomial
diarrhea. In an effort to understand the role of small noncoding RNAs (sRNAs) in C. difficile …

The pathogenic clostridia cause many human and animal diseases, which typically arise as
a consequence of the production of potent exotoxins. Among the enterotoxic clostridia …

Strains of Clostridioides difficile cause detrimental diarrheas with thousands of deaths
worldwide. The infection process by the Gram-positive, strictly anaerobic gut bacterium is …

The major virulence factors of Clostridium difficile are toxins A and B. These toxins are
encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with …

Clostridium difficile is a major cause of nosocomial infections. Bacterial persistence in the
gut is responsible for infection relapse; sporulation and other unidentified mechanisms …

Clostridium difficile is the largest single cause of hospital-acquired infection in the United
States. A major risk factor for Clostridium difficile infection (CDI) is prior exposure to …

To colonize the host and cause disease, the human enteropathogen Clostridioides difficile
must sense, respond, and adapt to the harsh environment of the gastrointestinal tract. We …

Endosporulation is an ancient bacterial developmental program that culminates with the
differentiation of a highly resistant endospore. In the model organism Bacillus subtilis, gene …